AutismKB 2.0

Annotation Details for ALOXE3


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Basic Information Top
Gene Symbol:ALOXE3 ( E-LOX,MGC119694,MGC119695,MGC119696,eLOX3 )
Gene Full Name: arachidonate lipoxygenase 3
Band: 17p13.1
Quick LinksEntrez ID:59344; OMIM: 607206; Uniprot ID:LOXE3_HUMAN; ENSEMBL ID: ENSG00000179148; HGNC ID: 13743
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0005506IEA-iron ion binding-
GO:0005515IPI-protein binding22622417
GO:0016702IDA-oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen20921226
GO:0016702IDANOToxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen12881489
GO:0016829IEA-lyase activity-
GO:0051120IDA-hepoxilin A3 synthase activity12881489
GO:0051120TAS-hepoxilin A3 synthase activity-
GO ID Evidence Qualifier GO_term References
GO:0006665IDA-sphingolipid metabolic process21558561
GO:0019233ISS-sensory perception of pain-
GO:0019369IDA-arachidonic acid metabolic process12881489
GO:0019372IDA-lipoxygenase pathway20921226
GO:0019372TAS-lipoxygenase pathway-
GO:0035357ISS-peroxisome proliferator activated receptor signaling pathway-
GO:0043651IDA-linoleic acid metabolic process12881489
GO:0045444ISS-fat cell differentiation-
GO:0046513ISS-ceramide biosynthetic process-
GO:0051122IDA-hepoxilin biosynthetic process12881489
GO:0055114IEA-oxidation-reduction process-
GO:0061436ISS-establishment of skin barrier-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1345140
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018