AutismKB 2.0

Annotation Details for RFC1


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Basic Information Top
Gene Symbol:RFC1 ( A1,MGC51786,MHCBFB,PO-GA,RECC1,RFC,RFC140 )
Gene Full Name: replication factor C (activator 1) 1, 145kDa
Band: 4p14
Quick LinksEntrez ID:5981; OMIM: 102579; Uniprot ID:RFC1_HUMAN; ENSEMBL ID: ENSG00000035928; HGNC ID: 9969
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005634IDA-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005663IDA-DNA replication factor C complex9488738
GO:0005730IEA-nucleolus-
GO:0005737IEA-cytoplasm-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003677IBA-DNA binding-
GO:0003689IEA-DNA clamp loader activity-
GO:0003690IEA-double-stranded DNA binding-
GO:0005515IPI-protein binding9488738
GO:0005524IEA-ATP binding-
GO:0008047TAS-enzyme activator activity8954124
GO:0019904IEA-protein domain specific binding-
GO:0043565IEA-sequence-specific DNA binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0000722TAS-telomere maintenance via recombination-
GO:0006261TAS-DNA-dependent DNA replication8248204
GO:0006283TAS-transcription-coupled nucleotide-excision repair-
GO:0006296TAS-nucleotide-excision repair, DNA incision, 5'-to lesion-
GO:0006297TAS-nucleotide-excision repair, DNA gap filling-
GO:0006351IEA-transcription, DNA-templated-
GO:0007004TAS-telomere maintenance via telomerase8954124
GO:0019985TAS-translesion synthesis-
GO:0033683TAS-nucleotide-excision repair, DNA incision-
GO:0042276TAS-error-prone translesion synthesis-
GO:0042769TAS-DNA damage response, detection of DNA damage-
GO:0043085IEA-positive regulation of catalytic activity-
GO:0045893IEA-positive regulation of transcription, DNA-templated-
GO:0070987TAS-error-free translesion synthesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RFC1ATM11191310783165 Co-purification
RFC1ATM10696210783165 Co-purification
RFC1CCND110706710353443 Affinity Capture-Western
RFC1CCND111191310353443 Affinity Capture-Western
RFC1BLM11191310783165 Co-purification
RFC1BLM10711010783165 Co-purification
RFC1BRCA110714010783165 Co-purification
RFC1BRCA111191310783165 Co-purification
RFC1CDK410745410353443 Affinity Capture-Western
RFC1CDK411191310353443 Affinity Capture-Western
RFC1MSH610921110783165 Co-purification
RFC1MSH611191310783165 Co-purification
RFC1HDAC110931512045192 Affinity Capture-Western; Reconstituted Complex
RFC1HDAC111191312045192 Affinity Capture-Western; Reconstituted Complex
RFC1KIT11001510353443 Affinity Capture-Western
RFC1KIT11191310353443 Affinity Capture-Western
RFC1MLH111043810783165 Co-purification
RFC1MLH111191310783165 Co-purification
RFC1MRE11A11191310783165 Co-purification
RFC1MRE11A11050110783165 Co-purification
RFC1MSH211057310783165 Co-purification
RFC1MSH211191310783165 Co-purification
RFC1NBN11076310783165 Co-purification
RFC1NBN11191310783165 Co-purification
RFC1PCNA1111428861969 8999859 10353443 12171929 12192049 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
RFC1PCNA1119138861969 8999859 10353443 12171929 12192049 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
RFC1PMS111191317148452 Affinity Capture-Western
RFC1PMS111139117148452 Affinity Capture-Western
RFC1RAD1711182118245774 Co-fractionation
RFC1RAD1711191318245774 Co-fractionation
RFC1RB111191310353443 Affinity Capture-Western
RFC1RB111186010353443 Affinity Capture-Western
RFC1RELA11191312509469 Affinity Capture-Western; Reconstituted Complex
RFC1RELA11190212509469 Affinity Capture-Western; Reconstituted Complex
RFC3RFC11119158692848 9488738 18245774 Affinity Capture-Western; Co-fractionation; Reconstituted Complex
RFC3RFC11119138692848 9488738 18245774 Affinity Capture-Western; Co-fractionation; Reconstituted Complex
SMARCA4RFC11119139443979 Co-fractionation
SMARCA4RFC11124819443979 Co-fractionation
RAD50RFC111191310783165 Co-purification
RAD50RFC111541710783165 Co-purification
BRD4RFC111703612192049 Affinity Capture-Western; Reconstituted Complex
BRD4RFC111191312192049 Affinity Capture-Western; Reconstituted Complex
XRCC5RFC111335312393188 Affinity Capture-Western
XRCC5RFC111191312393188 Affinity Capture-Western
TP53RFC111191312509469 Affinity Capture-Western
TP53RFC111301012509469 Affinity Capture-Western
SAP25RFC194101816449650 Affinity Capture-MS
SAP25RFC111191316449650 Affinity Capture-MS
RFC2RFC111191318245774 Co-fractionation
RFC2RFC111191418245774 Co-fractionation
RFC4RFC111191318245774 Co-fractionation
RFC4RFC111191618245774 Co-fractionation
RFC5RFC111191318245774 Co-fractionation
RFC5RFC111191718245774 Co-fractionation
CHTF18RFC111191318245774 Co-fractionation
CHTF18RFC112199118245774 Co-fractionation
SSBP3RFC111717520211142 Two-hybrid
SSBP3RFC111191320211142 Two-hybrid
ZSCAN1RFC112982520211142 Two-hybrid
ZSCAN1RFC111191320211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
RFC1RFC1_G80A Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:97891
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070410-99'