AutismKB 2.0

Annotation Details for RFX3


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Basic Information Top
Gene Symbol:RFX3 ( MGC87155,bA32F11.1 )
Gene Full Name: regulatory factor X, 3 (influences HLA class II expression)
Band: 9p24.2
Quick LinksEntrez ID:5991; OMIM: 601337; Uniprot ID:RFX3_HUMAN; ENSEMBL ID: ENSG00000080298; HGNC ID: 9984
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin20413507
GO:0005634IC-nucleus12411430
GO:0005667IC-transcription factor complex20413507
GO ID Evidence Qualifier GO_term References
GO:0000978IBA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0003677TAS-DNA binding8600444
GO:0003700NAS-transcription factor activity, sequence-specific DNA binding8600444
GO:0003705TAS-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding8289803
GO:0005515IPI-protein binding16189514
GO:0044212IDA-transcription regulatory region DNA binding20148032
GO ID Evidence Qualifier GO_term References
GO:0003309IBA-type B pancreatic cell differentiation-
GO:0006351IEA-transcription, DNA-templated-
GO:0006355ISS-regulation of transcription, DNA-templated-
GO:0031018ISS-endocrine pancreas development-
GO:0045892IDA-negative regulation of transcription, DNA-templated12411430
GO:0045893IDA-positive regulation of transcription, DNA-templated20148032
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter20413507
GO:0048469ISS-cell maturation20413507
GO:0050796ISS-regulation of insulin secretion20413507
GO:0060271IBA-cilium assembly-
GO:0060271ISS-cilium assembly20413507
GO:0060285ISS-cilium-dependent cell motility-
GO:0060287ISS-epithelial cilium movement involved in determination of left/right asymmetry-
GO:0072560IEA-type B pancreatic cell maturation-
GO:2000078ISS-positive regulation of type B pancreatic cell development20413507
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RFX3BIN111192320211142 Two-hybrid
RFX3BIN110677120211142 Two-hybrid
RFX3CREB111192320211142 Two-hybrid
RFX3CREB110777520211142 Two-hybrid
RFX3EWSR110843120211142 Two-hybrid
RFX3EWSR111192320211142 Two-hybrid
RFX3IRF610987220211142 Two-hybrid
RFX3IRF611192320211142 Two-hybrid
RFX3PKNOX111133320211142 Two-hybrid
RFX3PKNOX111192320211142 Two-hybrid
RFX4RFX311192311682486 Affinity Capture-Western
RFX4RFX311192411682486 Affinity Capture-Western
RFX6RFX312880316189514 Two-hybrid
RFX6RFX311192316189514 Two-hybrid
TRAF2RFX311192316189514 Two-hybrid
TRAF2RFX311303816189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:106582
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-061103-253'