AutismKB 2.0

Annotation Details for RGS1


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Basic Information Top
Gene Symbol:RGS1 ( 1R20,BL34,IER1,IR20 )
Gene Full Name: regulator of G-protein signaling 1
Band: 1q31.2
Quick LinksEntrez ID:5996; OMIM: 600323; Uniprot ID:RGS1_HUMAN; ENSEMBL ID: ENSG00000090104; HGNC ID: 9991
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829IDA-cytosol10480894
GO:0005886TAS-plasma membrane10480894
GO:0031234IDA-extrinsic component of cytoplasmic side of plasma membrane10480894
GO ID Evidence Qualifier GO_term References
GO:0001965IPI-G-protein alpha-subunit binding18434541
GO:0005096IDA-GTPase activator activity10480894
GO:0005516TAS-calmodulin binding10747990
GO ID Evidence Qualifier GO_term References
GO:0006955TAS-immune response8241276
GO:0007165IDA-signal transduction10480894
GO:0007186IDA-G-protein coupled receptor signaling pathway10480894
GO:0007193TAS-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway10480894
GO:0008277IEA-regulation of G-protein coupled receptor protein signaling pathway-
GO:0009968IEA-negative regulation of signal transduction-
GO:0043547IDA-positive regulation of GTPase activity10480894
GO:0061737IDA-leukotriene signaling pathway10480894
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
UTP14ARGS111602616169070 Two-hybrid
UTP14ARGS111192816169070 Two-hybrid
FUNDC2RGS112244016169070 Two-hybrid
FUNDC2RGS111192816169070 Two-hybrid
MAP3K12RGS111356616169070 Two-hybrid
MAP3K12RGS111192816169070 Two-hybrid
TSC22D1RGS111437416169070 Two-hybrid
TSC22D1RGS111192816169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1354694
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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