AutismKB 2.0

Annotation Details for RGS2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RGS2 ( G0S8 )
Gene Full Name: regulator of G-protein signaling 2, 24kDa
Band: 1q31.2
Quick LinksEntrez ID:5997; OMIM: 600861; Uniprot ID:RGS2_HUMAN; ENSEMBL ID: ENSG00000116741; HGNC ID: 9998
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10791963
GO:0005730IEA-nucleolus-
GO:0005737IDA-cytoplasm11278586
GO:0005739IEA-mitochondrion-
GO:0005829IDA-cytosol-
GO:0005829ISS-cytosol-
GO:0005886IDA-plasma membrane11278586
GO:0009898ISS-cytoplasmic side of plasma membrane-
GO:0043005IEA-neuron projection-
GO ID Evidence Qualifier GO_term References
GO:0001965IPI-G-protein alpha-subunit binding19478087
GO:0005096IMP-GTPase activator activity19478087
GO:0005515IPI-protein binding14608379
GO:0005516TAS-calmodulin binding10747990
GO:0048487IEA-beta-tubulin binding-
GO ID Evidence Qualifier GO_term References
GO:0006417IEA-regulation of translation-
GO:0007049IEA-cell cycle-
GO:0007283IEA-spermatogenesis-
GO:0008277IMP-regulation of G-protein coupled receptor protein signaling pathway19478087
GO:0010519ISS-negative regulation of phospholipase activity-
GO:0010614ISS-negative regulation of cardiac muscle hypertrophy-
GO:0031116IEA-positive regulation of microtubule polymerization-
GO:0043407ISS-negative regulation of MAP kinase activity-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0043951IEA-negative regulation of cAMP-mediated signaling-
GO:0045744ISS-negative regulation of G-protein coupled receptor protein signaling pathway-
GO:0050873IEA-brown fat cell differentiation-
GO:0055119ISS-relaxation of cardiac muscle-
GO:0060087IEA-relaxation of vascular smooth muscle-
GO:0060452ISS-positive regulation of cardiac muscle contraction-
GO:0071877ISS-regulation of adrenergic receptor signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RGS2ADCY510662412604604 Affinity Capture-Western; Reconstituted Complex
RGS2ADCY511192912604604 Affinity Capture-Western; Reconstituted Complex
RGS2DDR110723416169070 Two-hybrid
RGS2DDR111192916169070 Two-hybrid
RGS2GNA1510903112885252 Reconstituted Complex
RGS2GNA1511192912885252 Reconstituted Complex
RGS2GNAI31090359079700 Reconstituted Complex
RGS2GNAI31119299079700 Reconstituted Complex
RGS2GNAQ10903812885252 Reconstituted Complex
RGS2GNAQ11192912885252 Reconstituted Complex
RGS2GNAS1090409794454 Reconstituted Complex
RGS2GNAS1119299794454 Reconstituted Complex
RGS2HSPA811192916169070 Two-hybrid
RGS2HSPA810954416169070 Two-hybrid
RGS2EIF3E10985717353931 Affinity Capture-MS
RGS2EIF3E11192917353931 Affinity Capture-MS
RGS2PARK211192916169070 Two-hybrid
RGS2PARK211110516169070 Two-hybrid
RGS2PRKCA11192911063746 Biochemical Activity
RGS2PRKCA11156411063746 Biochemical Activity
RGS2PRKCB11192911063746 Biochemical Activity
RGS2PRKCB11156511063746 Biochemical Activity
RGS2PRKCG11192911063746 Biochemical Activity
RGS2PRKCG11156811063746 Biochemical Activity
RGS2PRKCSH11192916169070 Two-hybrid
RGS2PRKCSH11157516169070 Two-hybrid
RGS2PRKG111192914608379 Affinity Capture-Western; Reconstituted Complex
RGS2PRKG111157814608379 Affinity Capture-Western; Reconstituted Complex
GDE1RGS211192910760272 Reconstituted Complex; Two-hybrid
GDE1RGS211961810760272 Reconstituted Complex; Two-hybrid
COPB2RGS211469310982407 Co-fractionation
COPB2RGS211192910982407 Co-fractionation
GIT1RGS211192916169070 Two-hybrid
GIT1RGS211878916169070 Two-hybrid
VPS29RGS211968316169070 Two-hybrid
VPS29RGS211192916169070 Two-hybrid
WDR74RGS211192916169070 Two-hybrid
WDR74RGS212009216169070 Two-hybrid
ARFGAP1RGS211192916169070 Two-hybrid
ARFGAP1RGS212085616169070 Two-hybrid
LRFN1RGS212166816169070 Two-hybrid
LRFN1RGS211192916169070 Two-hybrid
NIPSNAP1RGS211408016169070 Two-hybrid
NIPSNAP1RGS211192916169070 Two-hybrid
DYNLL1RGS211420616169070 Two-hybrid
DYNLL1RGS211192916169070 Two-hybrid
NINLRGS211192916189514 Two-hybrid
NINLRGS211663016189514 Two-hybrid
IBTKRGS211192917353931 Affinity Capture-MS
IBTKRGS211747417353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1098271
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040718-410'