AutismKB 2.0

Annotation Details for ACTB


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ACTB ( PS1TP5BP1 )
Gene Full Name: actin, beta
Band: 7p22.1
Quick LinksEntrez ID:60; OMIM: 102630; Uniprot ID:ACTB_HUMAN; ENSEMBL ID: ENSG00000075624; HGNC ID: 132
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin16217013
GO:0005615IDA-extracellular space16502470
GO:0005654TAS-nucleoplasm-
GO:0005737TAS-cytoplasm16130169
GO:0005829TAS-cytosol-
GO:0005856ISS-cytoskeleton-
GO:0005856TAS-cytoskeleton16130169
GO:0005886ISS-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005925IDA-focal adhesion21423176
GO:0016020IDA-membrane19946888
GO:0030529IDA-intracellular ribonucleoprotein complex17289661
GO:0030863IEA-cortical cytoskeleton-
GO:0031982IDA-vesicle19190083
GO:0035267IDA-NuA4 histone acetyltransferase complex10966108
GO:0036464IDA-cytoplasmic ribonucleoprotein granule15121898
GO:0043209IEA-myelin sheath-
GO:0043234IDA-protein complex16217013
GO:0070062IDA-extracellular exosome11487543
GO:0072562IDA-blood microparticle22516433
GO:0097433ISS-dense body-
GO ID Evidence Qualifier GO_term References
GO:0000978IDAcontributes_toRNA polymerase II core promoter proximal region sequence-specific DNA binding16217013
GO:0000980IDAcontributes_toRNA polymerase II distal enhancer sequence-specific DNA binding16217013
GO:0005200TAS-structural constituent of cytoskeleton6202424
GO:0005515IPI-protein binding14592989
GO:0005524IEA-ATP binding-
GO:0019894IPI-kinesin binding18680169
GO:0030957IPI-Tat protein binding16687403
GO:0031492IDAcontributes_tonucleosomal DNA binding16217013
GO:0042802IPI-identical protein binding16189514
GO:0050998IPI-nitric-oxide synthase binding17502619
GO:0098973IDA-structural constituent of postsynaptic actin cytoskeleton18341992
GO ID Evidence Qualifier GO_term References
GO:0001895IEP-retina homeostasis23580065
GO:0006928TAS-movement of cell or subcellular component6202424
GO:0016579TAS-protein deubiquitination-
GO:0021762IEP-substantia nigra development22926577
GO:0034329TAS-cell junction assembly-
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0043044IDA-ATP-dependent chromatin remodeling16217013
GO:0045815TAS-positive regulation of gene expression, epigenetic-
GO:0048010TAS-vascular endothelial growth factor receptor signaling pathway-
GO:0048013TAS-ephrin receptor signaling pathway-
GO:0061024TAS-membrane organization-
GO:0070527IMP-platelet aggregation23382103
GO:0098974IDA-postsynaptic actin cytoskeleton organization18341992
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ACTBACTB1065759209005 16189514 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMARCE1ACTB1124899845365 18809673 Affinity Capture-MS; Affinity Capture-Western
SMARCE1ACTB1065759845365 18809673 Affinity Capture-MS; Affinity Capture-Western
SMARCA4ACTB1124819845365 Affinity Capture-Western
SMARCA4ACTB1065759845365 Affinity Capture-Western
SMARCC2ACTB1065759845365 Affinity Capture-Western
SMARCC2ACTB1124859845365 Affinity Capture-Western
PFN1ACTB11123710411937 Reconstituted Complex
PFN1ACTB10657510411937 Reconstituted Complex
NCF2ACTB11076811027608 Far Western
NCF2ACTB10657511027608 Far Western
RAC1ACTB10657511027608 Far Western
RAC1ACTB11181711027608 Far Western
RAC2ACTB10657511027608 Far Western
RAC2ACTB11181811027608 Far Western
NCF1ACTB57572411027608 Far Western
NCF1ACTB10657511027608 Far Western
SPTBN2ACTB10657511357136 11461920 Reconstituted Complex
SPTBN2ACTB11259011357136 11461920 Reconstituted Complex
CCT2ACTB11582711580269 Co-crystal Structure
CCT2ACTB10657511580269 Co-crystal Structure
CCT5ACTB11660311580269 Co-crystal Structure
CCT5ACTB10657511580269 Co-crystal Structure
PCYT1BACTB10657511580269 Co-crystal Structure
PCYT1BACTB11485411580269 Co-crystal Structure
SSH1ACTB11995011832213 Reconstituted Complex
SSH1ACTB10657511832213 Reconstituted Complex
SSH2ACTB12454811832213 Reconstituted Complex
SSH2ACTB10657511832213 Reconstituted Complex
MYCACTB11069411839798 Co-purification
MYCACTB10657511839798 Co-purification
RAB8BACTB10657512639940 Affinity Capture-Western
RAB8BACTB11971912639940 Affinity Capture-Western
CARM1ACTB11576014729568 Affinity Capture-Western; Co-purification
CARM1ACTB10657514729568 Affinity Capture-Western; Co-purification
CENPAACTB10748715009096 Co-purification
CENPAACTB10657515009096 Co-purification
NCALDACTB10657516189514 Affinity Capture-Western
NCALDACTB12383916189514 Affinity Capture-Western
CFL2ACTB10657516189514 Affinity Capture-Western; Two-hybrid
CFL2ACTB10750016189514 Affinity Capture-Western; Two-hybrid
CFL1ACTB10657516189514 Two-hybrid
CFL1ACTB10749916189514 Two-hybrid
DSTNACTB11622316189514 Two-hybrid
DSTNACTB10657516189514 Two-hybrid
ACTG1ACTB10658616189514 Two-hybrid
ACTG1ACTB10657516189514 Two-hybrid
MGMTACTB11041116226712 Affinity Capture-MS
MGMTACTB10657516226712 Affinity Capture-MS
EMDACTB10657517620012 Affinity Capture-MS
EMDACTB10832517620012 Affinity Capture-MS
RUVBL2ACTB10657517643375 Affinity Capture-MS
RUVBL2ACTB11606717643375 Affinity Capture-MS
MEPCEACTB12112217643375 Affinity Capture-MS
MEPCEACTB10657517643375 Affinity Capture-MS
RUVBL1ACTB10657517643375 Affinity Capture-MS
RUVBL1ACTB11416617643375 Affinity Capture-MS
BCL7CACTB11469118809673 Affinity Capture-MS
BCL7CACTB10657518809673 Affinity Capture-MS
PSTPIP1ACTB10657519041431 Affinity Capture-MS
PSTPIP1ACTB11451319041431 Affinity Capture-MS
INO80ACTB12007620197409 Affinity Capture-Western
INO80ACTB10657520197409 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:87904
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-000329-1'