Annotation Details for RGS12

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Basic Information Top

Gene Symbol:	RGS12 ( DKFZp761K1617,DKFZp761K1817 )
Gene Full Name:	regulator of G-protein signaling 12
Band:	4p16.3
Quick Links	Entrez ID:6002; OMIM: 602512; Uniprot ID:RGS12_HUMAN; ENSEMBL ID: ENSG00000159788; HGNC ID: 9994
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:12 results
Molecular Function:3 results
Biological Process:5 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0000794	TAS	-	condensed nuclear chromosome	10869340
GO:0005634	IDA	-	nucleus	-
GO:0005634	ISS	-	nucleus	-
GO:0005730	IDA	-	nucleolus	-
GO:0005737	IBA	-	cytoplasm	-
GO:0005737	ISS	-	cytoplasm	-
GO:0005829	IDA	-	cytosol	-
GO:0005886	IBA	-	plasma membrane	-
GO:0016363	IEA	-	nuclear matrix	-
GO:0030054	IEA	-	cell junction	-
GO:0030425	ISS	-	dendrite	-
GO:0045202	ISS	colocalizes_with	synapse	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0005057	IEA	-	signal transducer activity, downstream of receptor	-
GO:0005096	IBA	-	GTPase activator activity	-
GO:0030695	IDA	-	GTPase regulator activity	9651375

GO ID	Evidence	Qualifier	GO_term	References
GO:0006351	IEA	-	transcription, DNA-templated	-
GO:0007165	IEA	-	signal transduction	-
GO:0008277	TAS	-	regulation of G-protein coupled receptor protein signaling pathway	9651375
GO:0009968	IEA	-	negative regulation of signal transduction	-
GO:0043547	IEA	-	positive regulation of GTPase activity	-

Protein-Protein Interaction

BioGRID:6 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
RGS12	GNAI1	111934	11387333	Reconstituted Complex; Two-hybrid
RGS12	GNAI1	109032	11387333	Reconstituted Complex; Two-hybrid
RGS12	GNAI2	109033	11387333	Two-hybrid
RGS12	GNAI2	111934	11387333	Two-hybrid
RGS12	GNAI3	109035	11387333	Reconstituted Complex; Two-hybrid
RGS12	GNAI3	111934	11387333	Reconstituted Complex; Two-hybrid

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1918979
Data Attributes: MGI curated and HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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