Annotation Details for RHEB
Basic Information Top
| Gene Symbol: | RHEB ( MGC111559,RHEB2 ) |
|---|---|
| Gene Full Name: | Ras homolog enriched in brain |
| Band: | 7q36.1 |
| Quick Links | Entrez ID:6009; OMIM: 601293; Uniprot ID:RHEB_HUMAN; ENSEMBL ID: ENSG00000106615; HGNC ID: 10011 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000139 | IEA | - | Golgi membrane | - |
| GO:0005681 | IEA | - | spliceosomal complex | - |
| GO:0005765 | TAS | - | lysosomal membrane | - |
| GO:0005789 | IEA | - | endoplasmic reticulum membrane | - |
| GO:0005829 | IEA | - | cytosol | - |
| GO:0016020 | TAS | - | membrane | 8206940 |
| GO:0070062 | IDA | - | extracellular exosome | 19056867 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000287 | IMP | - | magnesium ion binding | 15728574 |
| GO:0003924 | TAS | - | GTPase activity | - |
| GO:0005525 | IMP | - | GTP binding | 15728574 |
| GO:0005525 | ISS | - | GTP binding | - |
| GO:0019003 | IMP | - | GDP binding | 15728574 |
| GO:0019901 | IEA | - | protein kinase binding | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0007050 | TAS | - | cell cycle arrest | - |
| GO:0007165 | IEA | - | signal transduction | - |
| GO:0016241 | TAS | - | regulation of macroautophagy | - |
| GO:0032008 | IMP | - | positive regulation of TOR signaling | 20381137 |
| GO:0048714 | IEA | - | positive regulation of oligodendrocyte differentiation | - |
| GO:2000074 | IMP | - | regulation of type B pancreatic cell development | 19258434 |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| RHEB | ATM | 111941 | 15854902 | Affinity Capture-Western; Reconstituted Complex |
| RHEB | ATM | 106962 | 15854902 | Affinity Capture-Western; Reconstituted Complex |
| RHEB | ATR | 107027 | 15854902 | Affinity Capture-Western; Reconstituted Complex |
| RHEB | ATR | 111941 | 15854902 | Affinity Capture-Western; Reconstituted Complex |
| RHEB | MTOR | 108757 | 15772076 15854902 15878852 16915281 | Affinity Capture-Western; Reconstituted Complex |
| RHEB | MTOR | 111941 | 15772076 15854902 15878852 16915281 | Affinity Capture-Western; Reconstituted Complex |
| RHEB | HRAS | 109501 | 15854902 | Affinity Capture-Western |
| RHEB | HRAS | 111941 | 15854902 | Affinity Capture-Western |
| RHEB | PDE6D | 111941 | 11980706 | Two-hybrid |
| RHEB | PDE6D | 111173 | 11980706 | Two-hybrid |
| RHEB | RAF1 | 111831 | 9001246 15150271 15854902 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
| RHEB | RAF1 | 111941 | 9001246 15150271 15854902 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
| RHEB | RAP1A | 111841 | 15854902 | Affinity Capture-Western |
| RHEB | RAP1A | 111941 | 15854902 | Affinity Capture-Western |
| TSC2 | RHEB | 113100 | 12771962 12820960 12842888 12869586 15854902 17077083 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
| TSC2 | RHEB | 111941 | 12771962 12820960 12842888 12869586 15854902 17077083 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
| TSC1 | RHEB | 113099 | 12820960 | Biochemical Activity |
| TSC1 | RHEB | 111941 | 12820960 | Biochemical Activity |
| RAB7A | RHEB | 113624 | 15809346 | Co-localization |
| RAB7A | RHEB | 111941 | 15809346 | Co-localization |
| RAB9A | RHEB | 114768 | 15809346 | Co-localization |
| RAB9A | RHEB | 111941 | 15809346 | Co-localization |
| RPTOR | RHEB | 111941 | 15854902 | Affinity Capture-Western; Reconstituted Complex |
| RPTOR | RHEB | 121582 | 15854902 | Affinity Capture-Western; Reconstituted Complex |
| No data |
| No data |
AlzGene, PDGene and SZGene