AutismKB 2.0

Annotation Details for APOBEC3G


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Basic Information Top
Gene Symbol:APOBEC3G ( ARCD,ARP-9,ARP9,CEM-15,CEM15,FLJ12740,bK150C2.7,dJ494G10.1 )
Gene Full Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
Band: 22q13.1
Quick LinksEntrez ID:60489; OMIM: 607113; Uniprot ID:ABC3G_HUMAN; ENSEMBL ID: ENSG00000128394; HGNC ID: 17357
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000932IDA-P-body16699599
GO:0005737IDA-cytoplasm16527742
GO:0005829TAS-cytosol-
GO:0030529IDA-intracellular ribonucleoprotein complex16699599
GO:0030895TAS-apolipoprotein B mRNA editing enzyme complex17121840
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding11863358
GO:0004126TAS-cytidine deaminase activity17121840
GO:0005515IPI-protein binding16699599
GO:0008270IDA-zinc ion binding11863358
GO:0008829TAS-dCTP deaminase activity-
GO:0042803NAS-protein homodimerization activity11863358
GO:0047844IDA-deoxycytidine deaminase activity12808465
GO ID Evidence Qualifier GO_term References
GO:0002230IDA-positive regulation of defense response to virus by host17121840
GO:0009972IDA-cytidine deamination16378963
GO:0010529IDA-negative regulation of transposition16527742
GO:0016553TAS-base conversion or substitution editing17121840
GO:0045071IDA-negative regulation of viral genome replication16378963
GO:0045087IDA-innate immune response17121840
GO:0045869IDA-negative regulation of single stranded viral RNA replication via double stranded DNA intermediate16571802
GO:0048525IDA-negative regulation of viral process17121840
GO:0051607IDA-defense response to virus12808465
GO:0070383IDA-DNA cytosine deamination16527742
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
APOBEC3GPRKACA11155318836454 Affinity Capture-Western; Biochemical Activity
APOBEC3GPRKACA12192018836454 Affinity Capture-Western; Biochemical Activity
APOBEC3GPTN12192016169070 Two-hybrid
APOBEC3GPTN11173116169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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