AutismKB 2.0

Annotation Details for ROBO2


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Basic Information Top
Gene Symbol:ROBO2 ( KIAA1568,SAX3 )
Gene Full Name: roundabout, axon guidance receptor, homolog 2 (Drosophila)
Band: 3p12.3
Quick LinksEntrez ID:6092; OMIM: 602431; Uniprot ID:ROBO2_HUMAN; ENSEMBL ID: ENSG00000185008; HGNC ID: 10250
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0009986IDA-cell surface12504588
GO:0016021IEA-integral component of membrane-
GO:0030673ISS-axolemma-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding12504588
GO:0008046ISS-axon guidance receptor activity-
GO:0008046NAS-axon guidance receptor activity9458045
GO:0042802IDA-identical protein binding12504588
GO ID Evidence Qualifier GO_term References
GO:0001656ISS-metanephros development-
GO:0001657IMP-ureteric bud development17357069
GO:0007156IDA-homophilic cell adhesion via plasma membrane adhesion molecules12504588
GO:0007411ISS-axon guidance-
GO:0007417NAS-central nervous system development9458045
GO:0007420IEP-brain development10197527
GO:0016199ISS-axon midline choice point recognition-
GO:0021510IEA-spinal cord development-
GO:0021891ISS-olfactory bulb interneuron development-
GO:0031290ISS-retinal ganglion cell axon guidance-
GO:0032870IEP-cellular response to hormone stimulus18566128
GO:0035385IEA-Roundabout signaling pathway-
GO:0050772IDA-positive regulation of axonogenesis12504588
GO:0050925IDA-negative regulation of negative chemotaxis11748139
GO:0051964ISS-negative regulation of synapse assembly-
GO:0061364IEP-apoptotic process involved in luteolysis18566128
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ROBO2CPE10775516169070 Two-hybrid
ROBO2CPE11201916169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1890110
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-001019-1'