AutismKB 2.0

Annotation Details for RPS6KA3


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Basic Information Top
Gene Symbol:RPS6KA3 ( CLS,HU-3,ISPK-1,MAPKAPK1B,MRX19,RSK,RSK2,S6K-alpha3,p90-RSK2,pp90RSK2 )
Gene Full Name: ribosomal protein S6 kinase, 90kDa, polypeptide 3
Band: Xp22.12
Quick LinksEntrez ID:6197; OMIM: 300075; Uniprot ID:KS6A3_HUMAN; ENSEMBL ID: ENSG00000177189; HGNC ID: 10432
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005737IBA-cytoplasm-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0000287IEA-magnesium ion binding-
GO:0004672TAS-protein kinase activity10436156
GO:0004674IBA-protein serine/threonine kinase activity-
GO:0004674TAS-protein serine/threonine kinase activity-
GO:0005515IPI-protein binding21988832
GO:0005524IEA-ATP binding-
GO:0016301TAS-kinase activity-
GO:0019901IEA-protein kinase binding-
GO:0043027IDA-cysteine-type endopeptidase inhibitor activity involved in apoptotic process18402937
GO ID Evidence Qualifier GO_term References
GO:0001501TAS-skeletal system development8955270
GO:0002224ISS-toll-like receptor signaling pathway-
GO:0006915IEA-apoptotic process-
GO:0007049IEA-cell cycle-
GO:0007165TAS-signal transduction10436156
GO:0007417TAS-central nervous system development10319851
GO:0018105TAS-peptidyl-serine phosphorylation11404397
GO:0030307TAS-positive regulation of cell growth18813292
GO:0032496ISS-response to lipopolysaccharide-
GO:0035556IBA-intracellular signal transduction-
GO:0043066TAS-negative regulation of apoptotic process18813292
GO:0043154IDA-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process18402937
GO:0043555TAS-regulation of translation in response to stress18813292
GO:0043620TAS-regulation of DNA-templated transcription in response to stress18813292
GO:0045597TAS-positive regulation of cell differentiation18813292
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter22065586
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RPS6KA3CREBBP11211111564891 Affinity Capture-Western; Phenotypic Suppression
RPS6KA3CREBBP10777711564891 Affinity Capture-Western; Phenotypic Suppression
RPS6KA3MAPK1411211111157753 Affinity Capture-Western
RPS6KA3MAPK1410781911157753 Affinity Capture-Western
RPS6KA3PDPK111211110856237 Affinity Capture-Western
RPS6KA3PDPK111119610856237 Affinity Capture-Western
RPS6KA3MAPK11121118939914 9915826 Affinity Capture-Western
RPS6KA3MAPK11115808939914 9915826 Affinity Capture-Western
RPS6KA3MAPK31115818939914 Affinity Capture-Western
RPS6KA3MAPK31121118939914 Affinity Capture-Western
PEA15RPS6KA311211112796492 Affinity Capture-Western; Reconstituted Complex
PEA15RPS6KA311423012796492 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104557
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030219-119'