AutismKB 2.0

Annotation Details for RREB1


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Basic Information Top
Gene Symbol:RREB1 ( FINB,HNT,LZ321,RREB-1,Zep-1 )
Gene Full Name: ras responsive element binding protein 1
Band: 6p24.3
Quick LinksEntrez ID:6239; OMIM: 602209; Uniprot ID:RREB1_HUMAN; ENSEMBL ID: ENSG00000124782; HGNC ID: 10449
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001650IDA-fibrillar center-
GO:0005634TAS-nucleus9305772
GO:0005737TAS-cytoplasm9305772
GO:0016604TAS-nuclear body9305772
GO:0016607IDA-nuclear speck-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding8816445
GO:0000979IMP-RNA polymerase II core promoter sequence-specific DNA binding20133935
GO:0001228IDA-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding8816445
GO:0003700IBA-transcription factor activity, sequence-specific DNA binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter20133935
GO:0006355TAS-regulation of transcription, DNA-templated9305772
GO:0006366TAS-transcription from RNA polymerase II promoter8816445
GO:0007265TAS-Ras protein signal transduction8816445
GO:0007275TAS-multicellular organism development8816445
GO:0010634IMP-positive regulation of epithelial cell migration18394891
GO:0033601IMP-positive regulation of mammary gland epithelial cell proliferation18394891
GO:0045893TAS-positive regulation of transcription, DNA-templated9305772
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter8816445
GO:1900026IMP-positive regulation of substrate adhesion-dependent cell spreading18394891
GO:1903691IMP-positive regulation of wound healing, spreading of epidermal cells18394891
GO:2000394IMP-positive regulation of lamellipodium morphogenesis18394891
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RREB1CTBP111215317967884 Affinity Capture-Western
RREB1CTBP110786917967884 Affinity Capture-Western
KDM1ARREB111215316140033 Affinity Capture-MS
KDM1ARREB111666716140033 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2443664
  • Data Attributes: HomoloGene calculated
No data