AutismKB 2.0

Annotation Details for RRM1


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Basic Information Top
Gene Symbol:RRM1 ( R1,RIR1,RR1 )
Gene Full Name: ribonucleotide reductase M1
Band: 11p15.4
Quick LinksEntrez ID:6240; OMIM: 180410; Uniprot ID:RIR1_HUMAN; ENSEMBL ID: ENSG00000167325; HGNC ID: 10451
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005635IEA-nuclear envelope-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005971IEA-ribonucleoside-diphosphate reductase complex-
GO:0042995IEA-cell projection-
GO:0043025IEA-neuronal cell body-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0004748ISS-ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor-
GO:0005515IPI-protein binding22632967
GO:0005524IEA-ATP binding-
GO:0097718IEA-disordered domain specific binding-
GO ID Evidence Qualifier GO_term References
GO:0000278IEA-mitotic cell cycle-
GO:0006206IEA-pyrimidine nucleobase metabolic process-
GO:0006260IEA-DNA replication-
GO:0008584IEA-male gonad development-
GO:0009263ISS-deoxyribonucleotide biosynthetic process-
GO:0010212IEA-response to ionizing radiation-
GO:0015949TAS-nucleobase-containing small molecule interconversion-
GO:0021846IEA-cell proliferation in forebrain-
GO:0051290IEA-protein heterotetramerization-
GO:0055114IEA-oxidation-reduction process-
GO:0060041IEA-retina development in camera-type eye-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RRM2RRM111215511781084 14583450 Affinity Capture-Western; Reconstituted Complex
RRM2RRM111215411781084 14583450 Affinity Capture-Western; Reconstituted Complex
RRM1RRM111215411781084 Reconstituted Complex
RRM2BRRM111907114583450 Affinity Capture-Western
RRM2BRRM111215414583450 Affinity Capture-Western
C1orf103RRM111215416169070 Two-hybrid
C1orf103RRM112090516169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98180
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-247'