AutismKB 2.0

Annotation Details for RRM2


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Basic Information Top
Gene Symbol:RRM2 ( R2,RR2,RR2M )
Gene Full Name: ribonucleotide reductase M2
Band: 2p25.1
Quick LinksEntrez ID:6241; OMIM: 180390; Uniprot ID:RIR2_HUMAN; ENSEMBL ID: ENSG00000171848; HGNC ID: 10452
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005971IEA-ribonucleoside-diphosphate reductase complex-
GO ID Evidence Qualifier GO_term References
GO:0004748IBA-ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor-
GO:0004748ISS-ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor-
GO:0004748NAS-ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor1627826
GO:0005515IPI-protein binding22632967
GO:0008199IEA-ferric iron binding-
GO:0042803IEA-protein homodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0000083TAS-regulation of transcription involved in G1/S transition of mitotic cell cycle-
GO:0006260IEA-DNA replication-
GO:0009263IBA-deoxyribonucleotide biosynthetic process-
GO:0009263ISS-deoxyribonucleotide biosynthetic process-
GO:0015949TAS-nucleobase-containing small molecule interconversion-
GO:0051290IEA-protein heterotetramerization-
GO:0055114IEA-oxidation-reduction process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RRM2RRM111215511781084 14583450 Affinity Capture-Western; Reconstituted Complex
RRM2RRM111215411781084 14583450 Affinity Capture-Western; Reconstituted Complex
TP53RRM211215512615712 Affinity Capture-Western
TP53RRM211301012615712 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98181
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-25'