AutismKB 2.0

Annotation Details for BDNF


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Basic Information Top
Gene Symbol:BDNF ( MGC34632 )
Gene Full Name: brain-derived neurotrophic factor
Band: 11p14.1
Quick LinksEntrez ID:627; OMIM: 113505; Uniprot ID:BDNF_HUMAN; ENSEMBL ID: ENSG00000176697; HGNC ID: 1033
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IBA-extracellular region-
GO:0005737ISS-cytoplasm-
GO:0005739IDA-mitochondrion-
GO:0016607IDA-nuclear speck-
GO:0031410IBA-cytoplasmic vesicle-
GO:0048471ISS-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0005169IBA-neurotrophin TRKB receptor binding-
GO:0008083IBA-growth factor activity-
GO ID Evidence Qualifier GO_term References
GO:0007267IBA-cell-cell signaling-
GO:0007399TAS-nervous system development2236018
GO:0007411TAS-axon guidance19036963
GO:0007416IDA-synapse assembly19036963
GO:0010832ISS-negative regulation of myotube differentiation-
GO:0031547TAS-brain-derived neurotrophic factor receptor signaling pathway19036963
GO:0031550TAS-positive regulation of brain-derived neurotrophic factor receptor signaling pathway19036963
GO:0043524IBA-negative regulation of neuron apoptotic process-
GO:0048668IDA-collateral sprouting19036963
GO:0048672IDA-positive regulation of collateral sprouting19036963
GO:0051965IDA-positive regulation of synapse assembly19036963
GO:1900122IDA-positive regulation of receptor binding12130635
GO:2000008TAS-regulation of protein localization to cell surface12130635
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NTRK2BDNF1109709312147 11855816 Reconstituted Complex
NTRK2BDNF1070969312147 11855816 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
BDNFBDNF_270C/T, G-712A, SNP5, rs1048218, rs1048220, rs1048221, rs11030104, rs11030121, rs2030324, rs2049045, rs2049046, rs2203877, rs6265, rs7103411, rs7124442, rs8192466 Gene overview in AlzGene
Gene Symbol Poly Names Gene overview in PDGene
BDNFBDNF_-1331C/T, BDNF_270C/T, D11S4115, rs11030104, rs11030121, rs11267088, rs2030224, rs2049045, rs2049046, rs3088390, rs6265, rs7103411, rs7124442, rs7127507 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
BDNFBDNF_-270C/T, BDNF_132C/T, BDNF_712G/A, BDNF_STR-down, BDNF_STR-up, ro_000011924, rs11030101, rs11030104, rs11030121, rs12273363, rs12291063, rs1491851, rs1519480, rs16917204, rs2030324, rs2049045, rs2883187, rs3750934, rs4923463, rs6265, rs7103411, rs7127507, rs71971022, rs7934165, rs908867, rs988748 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:88145
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-000412-1'