AutismKB 2.0

Annotation Details for MAPK12


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Basic Information Top
Gene Symbol:MAPK12 ( ERK3,ERK6,P38GAMMA,PRKM12,SAPK-3,SAPK3 )
Gene Full Name: mitogen-activated protein kinase 12
Band: 22q13.33
Quick LinksEntrez ID:6300; OMIM: 602399; Uniprot ID:MK12_HUMAN; ENSEMBL ID: ENSG00000188130; HGNC ID: 6874
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005737IBA-cytoplasm-
GO:0005739IEA-mitochondrion-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0000287IDA-magnesium ion binding10508788
GO:0004674IDA-protein serine/threonine kinase activity8633070
GO:0004674TAS-protein serine/threonine kinase activity18221368
GO:0004707IBA-MAP kinase activity-
GO:0005515IPI-protein binding12761180
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0000165IEA-MAPK cascade-
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0006975TAS-DNA damage induced protein phosphorylation10848581
GO:0007050TAS-cell cycle arrest10848581
GO:0007165TAS-signal transduction8633070
GO:0007517TAS-muscle organ development8633070
GO:0010468IBA-regulation of gene expression-
GO:0010952NAS-positive regulation of peptidase activity18221368
GO:0018105IDA-peptidyl-serine phosphorylation15850461
GO:0018105TAS-peptidyl-serine phosphorylation18221368
GO:0035556IBA-intracellular signal transduction-
GO:0045445IDA-myoblast differentiation8633070
GO:0048010TAS-vascular endothelial growth factor receptor signaling pathway-
GO:0051149TAS-positive regulation of muscle cell differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SNTA1MAPK1211220710212242 Affinity Capture-Western; Biochemical Activity; Two-hybrid
SNTA1MAPK1211252310212242 Affinity Capture-Western; Biochemical Activity; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1353438
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-257'