AutismKB 2.0

Annotation Details for SERPINB4


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Basic Information Top
Gene Symbol:SERPINB4 ( LEUPIN,PI11,SCCA-2,SCCA1,SCCA2 )
Gene Full Name: serpin peptidase inhibitor, clade B (ovalbumin), member 4
Band: 18q21.33
Quick LinksEntrez ID:6318; OMIM: 600518; Uniprot ID:SPB4_HUMAN; ENSEMBL ID: ENSG00000206073; HGNC ID: 10570
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IBA-extracellular space-
GO:0005622IDA-intracellular21857942
GO:0005737IEA-cytoplasm-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0002020IPI-protease binding21857942
GO:0004867IDA-serine-type endopeptidase inhibitor activity21857942
GO:0004867NAS-serine-type endopeptidase inhibitor activity7589435
GO:0019899IPI-enzyme binding23382074
GO ID Evidence Qualifier GO_term References
GO:0010466IDA-negative regulation of peptidase activity12949073
GO:0010951IEA-negative regulation of endopeptidase activity-
GO:0030162NAS-regulation of proteolysis7589435
GO:0042270IMP-protection from natural killer cell mediated cytotoxicity21857942
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
USF2SERPINB411323817353931 Affinity Capture-MS
USF2SERPINB411222417353931 Affinity Capture-MS
BTRCSERPINB411222419615732 Affinity Capture-MS
BTRCSERPINB411445719615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018