AutismKB 2.0

Annotation Details for CCL20


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Basic Information Top
Gene Symbol:CCL20 ( CKb4,LARC,MIP-3a,MIP3A,SCYA20,ST38 )
Gene Full Name: chemokine (C-C motif) ligand 20
Band: 2q36.3
Quick LinksEntrez ID:6364; OMIM: 601960; Uniprot ID:CCL20_HUMAN; ENSEMBL ID: ENSG00000115009; HGNC ID: 10619
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IBA-extracellular space-
GO:0005622IEA-intracellular-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding17703191
GO:0008009IBA-chemokine activity-
GO:0031731IDA-CCR6 chemokine receptor binding12081481
GO ID Evidence Qualifier GO_term References
GO:0002548IBA-monocyte chemotaxis-
GO:0006935IDA-chemotaxis20068036
GO:0006954IBA-inflammatory response-
GO:0006955TAS-immune response10521347
GO:0007165TAS-signal transduction9038201
GO:0007186IBA-G-protein coupled receptor signaling pathway-
GO:0007267TAS-cell-cell signaling9038201
GO:0030593IBA-neutrophil chemotaxis-
GO:0035584IDA-calcium-mediated signaling using intracellular calcium source25122636
GO:0042060IEA-wound healing-
GO:0042742IEA-defense response to bacterium-
GO:0043547IBA-positive regulation of GTPase activity-
GO:0048247IBA-lymphocyte chemotaxis-
GO:0050726IEA-positive regulation of interleukin-1 alpha biosynthetic process-
GO:0051770IEA-positive regulation of nitric-oxide synthase biosynthetic process-
GO:0060326IDA-cell chemotaxis23765988
GO:0070098IBA-chemokine-mediated signaling pathway-
GO:0070374IBA-positive regulation of ERK1 and ERK2 cascade-
GO:0071222IEA-cellular response to lipopolysaccharide-
GO:0071223IEA-cellular response to lipoteichoic acid-
GO:0071346IBA-cellular response to interferon-gamma-
GO:0071347IBA-cellular response to interleukin-1-
GO:0071356IBA-cellular response to tumor necrosis factor-
GO:0072678ISS-T cell migration-
GO:0072679ISS-thymocyte migration-
GO:2000406IDA-positive regulation of T cell migration23620790
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CCL20CCR61122679169459 Reconstituted Complex
CCL20CCR61076409169459 Reconstituted Complex
CCL20VCAN11226711083865 Reconstituted Complex
CCL20VCAN10784411083865 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1329031
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018