AutismKB 2.0

Annotation Details for CCL22


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Basic Information Top
Gene Symbol:CCL22 ( ABCD-1,DC/B-CK,MDC,MGC34554,SCYA22,STCP-1 )
Gene Full Name: chemokine (C-C motif) ligand 22
Band: 16q21
Quick LinksEntrez ID:6367; OMIM: 602957; Uniprot ID:CCL22_HUMAN; ENSEMBL ID: ENSG00000102962; HGNC ID: 10621
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IBA-extracellular space-
GO ID Evidence Qualifier GO_term References
GO:0008009IBA-chemokine activity-
GO:0048020IBA-CCR chemokine receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0002548IBA-monocyte chemotaxis-
GO:0006935TAS-chemotaxis10861057
GO:0006954IBA-inflammatory response-
GO:0006955TAS-immune response10861057
GO:0007165TAS-signal transduction9743322
GO:0007186IBA-G-protein coupled receptor signaling pathway-
GO:0007267TAS-cell-cell signaling9151897
GO:0009615TAS-response to virus9381181
GO:0030593IBA-neutrophil chemotaxis-
GO:0043547IBA-positive regulation of GTPase activity-
GO:0048247IBA-lymphocyte chemotaxis-
GO:0070098IBA-chemokine-mediated signaling pathway-
GO:0070374IBA-positive regulation of ERK1 and ERK2 cascade-
GO:0071346IBA-cellular response to interferon-gamma-
GO:0071347IBA-cellular response to interleukin-1-
GO:0071356IBA-cellular response to tumor necrosis factor-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CCL22CCR41122709430724 Reconstituted Complex
CCL22CCR41076389430724 Reconstituted Complex
CCL22DPP41122709933589 Biochemical Activity
CCL22DPP41081379933589 Biochemical Activity
VCAM1CCL2211227012193695 Reconstituted Complex
VCAM1CCL2211325512193695 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1306779
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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