AutismKB 2.0

Annotation Details for BID


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Basic Information Top
Gene Symbol:BID ( FP497,MGC15319,MGC42355 )
Gene Full Name: BH3 interacting domain death agonist
Band: 22q11.21
Quick LinksEntrez ID:637; OMIM: 601997; Uniprot ID:BID_HUMAN; ENSEMBL ID: ENSG00000015475; HGNC ID: 1050
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739TAS-mitochondrion9727491
GO:0005741TAS-mitochondrial outer membrane-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0016020TAS-membrane8918887
GO:0032592IEA-integral component of mitochondrial membrane-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005123TAS-death receptor binding8918887
GO:0005515IPI-protein binding9463381
GO:0031625IEA-ubiquitin protein ligase binding-
GO:0046982IEA-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0001836IDA-release of cytochrome c from mitochondria17052454
GO:0006626IEA-protein targeting to mitochondrion-
GO:0006919IEA-activation of cysteine-type endopeptidase activity involved in apoptotic process-
GO:0007420IEA-brain development-
GO:0008625TAS-extrinsic apoptotic signaling pathway via death domain receptors9727491
GO:0008637TAS-apoptotic mitochondrial changes9727492
GO:0010918IEA-positive regulation of mitochondrial membrane potential-
GO:0032355IEA-response to estradiol-
GO:0032461IDA-positive regulation of protein oligomerization19074440
GO:0032464IDA-positive regulation of protein homooligomerization21041309
GO:0034349IEA-glial cell apoptotic process-
GO:0042127IEA-regulation of cell proliferation-
GO:0042770TAS-signal transduction in response to DNA damage18309324
GO:0042775IEA-mitochondrial ATP synthesis coupled electron transport-
GO:0042981TAS-regulation of apoptotic process-
GO:0043065IMP-positive regulation of apoptotic process17289999
GO:0051260IEA-protein homooligomerization-
GO:0051402TAS-neuron apoptotic process16167175
GO:0090150IDA-establishment of protein localization to membrane21041309
GO:0090200IGI-positive regulation of release of cytochrome c from mitochondria21041309
GO:0090200IMP-positive regulation of release of cytochrome c from mitochondria17289999
GO:0097284IEA-hepatocyte apoptotic process-
GO:0097345IEA-mitochondrial outer membrane permeabilization-
GO:1900740TAS-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-
GO:1901030TAS-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-
GO:1902230IEA-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-
GO:2000045IEA-regulation of G1/S transition of mitotic cell cycle-
GO:2000271IEA-positive regulation of fibroblast apoptotic process-
GO:2001238IMP-positive regulation of extrinsic apoptotic signaling pathway21459798
GO:2001244TAS-positive regulation of intrinsic apoptotic signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BIDFAS10685115659383 Co-purification
BIDFAS10710615659383 Co-purification
BIDFASLG10685215659383 Co-purification
BIDFASLG10710615659383 Co-purification
BIDRHOA10688015659383 Co-purification
BIDRHOA10710615659383 Co-purification
BIDARHGDIA10688915659383 Co-purification
BIDARHGDIA10710615659383 Co-purification
BIDBCL210706815520201 15694340 Protein-peptide
BIDBCL210710615520201 15694340 Protein-peptide
BIDBCL2A110706911929871 Affinity Capture-Western
BIDBCL2A110710611929871 Affinity Capture-Western
BIDBCL2L110707015694340 Protein-peptide
BIDBCL2L110710615694340 Protein-peptide
BIDBCL2L210710615694340 Protein-peptide
BIDBCL2L210707115694340 Protein-peptide
CASP2BID10728511399776 11832478 Biochemical Activity
CASP2BID10710611399776 11832478 Biochemical Activity
CASP3BID10728611399776 Biochemical Activity
CASP3BID10710611399776 Biochemical Activity
BIDBID10710611805084 Affinity Capture-Western
CASP8BID10729111832478 15659383 Biochemical Activity; Co-purification
CASP8BID10710611832478 15659383 Biochemical Activity; Co-purification
CAPN2BID10710612000759 Biochemical Activity
CAPN2BID10727412000759 Biochemical Activity
MCL1BID10710615637055 15694340 Affinity Capture-Western; Protein-peptide; Reconstituted Complex
MCL1BID11033815637055 15694340 Affinity Capture-Western; Protein-peptide; Reconstituted Complex
MSNBID10710615659383 Co-purification
MSNBID11058415659383 Co-purification
MAPK8BID11158515659383 Co-purification
MAPK8BID10710615659383 Co-purification
TNFRSF1ABID11298615659383 Co-purification
TNFRSF1ABID10710615659383 Co-purification
EZRBID11327115659383 Co-purification
EZRBID10710615659383 Co-purification
CASP10BID10710615659383 Co-purification
CASP10BID10729315659383 Co-purification
FADDBID11430215659383 Co-purification
FADDBID10710615659383 Co-purification
TNFRSF10BBID11432315659383 Co-purification
TNFRSF10BBID10710615659383 Co-purification
Gene Symbol Interactant Interaction ID References Description
BIDBCL219317715574335 Bid interacts with Bcl-2.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:108093
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050419-35'