AutismKB 2.0

Annotation Details for BIK


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Basic Information Top
Gene Symbol:BIK ( BIP1,BP4,NBK )
Gene Full Name: BCL2-interacting killer (apoptosis-inducing)
Band: 22q13.2
Quick LinksEntrez ID:638; OMIM: 603392; Uniprot ID:BIK_HUMAN; ENSEMBL ID: ENSG00000100290; HGNC ID: 1051
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0012505IEA-endomembrane system-
GO:0016021IEA-integral component of membrane-
GO:0031966IEA-mitochondrial membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding9463381
GO:0046982IEA-protein heterodimerization activity-
GO:0051400IEA-BH domain binding-
GO ID Evidence Qualifier GO_term References
GO:0006915TAS-apoptotic process10381623
GO:0007283IEA-spermatogenesis-
GO:0008584IEA-male gonad development-
GO:0008637IEA-apoptotic mitochondrial changes-
GO:0032464IDA-positive regulation of protein homooligomerization21041309
GO:0090200IDA-positive regulation of release of cytochrome c from mitochondria21041309
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BIKBCL210706812853473 15694340 Affinity Capture-Western; Protein-peptide
BIKBCL210710712853473 15694340 Affinity Capture-Western; Protein-peptide
BIKBCL2A110706915694340 Protein-peptide
BIKBCL2A110710715694340 Protein-peptide
BIKBCL2L110707011342619 12853473 15694340 16189514 Affinity Capture-Western; Protein-peptide; Two-hybrid
BIKBCL2L110710711342619 12853473 15694340 16189514 Affinity Capture-Western; Protein-peptide; Two-hybrid
BIKBCL2L210710710381646 Affinity Capture-Western
BIKBCL2L210707110381646 Affinity Capture-Western
MCL1BIK10710715694340 Protein-peptide
MCL1BIK11033815694340 Protein-peptide
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
BIKrs11090143, rs2235316, rs4988372, rs4988374, rs926328 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1206591
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041210-181'