AutismKB 2.0

Annotation Details for PRDM1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PRDM1 ( BLIMP1,MGC118922,MGC118923,MGC118924,MGC118925,PRDI-BF1 )
Gene Full Name: PR domain containing 1, with ZNF domain
Band: 6q21
Quick LinksEntrez ID:639; OMIM: 603423; Uniprot ID:PRDM1_HUMAN; ENSEMBL ID: ENSG00000057657; HGNC ID: 9346
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm21421998
GO ID Evidence Qualifier GO_term References
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding1851123
GO:0001078IDA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding1851123
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding1851123
GO:0005515IPI-protein binding22555612
GO:0008168IEA-methyltransferase activity-
GO:0042826IEA-histone deacetylase binding-
GO:0046872IEA-metal ion binding-
GO:1990841ISS-promoter-specific chromatin binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter1851123
GO:0001763IEA-morphogenesis of a branching structure-
GO:0001893IEA-maternal placenta development-
GO:0002250IEA-adaptive immune response-
GO:0003170IEA-heart valve development-
GO:0003281IEA-ventricular septum development-
GO:0006351IEA-transcription, DNA-templated-
GO:0007281IEA-germ cell development-
GO:0009791IEA-post-embryonic development-
GO:0010628IEA-positive regulation of gene expression-
GO:0030889IEA-negative regulation of B cell proliferation-
GO:0031665IEA-negative regulation of lipopolysaccharide-mediated signaling pathway-
GO:0032259IEA-methylation-
GO:0032823ISS-regulation of natural killer cell differentiation-
GO:0033082ISS-regulation of extrathymic T cell differentiation-
GO:0035904IEA-aorta development-
GO:0042462IEA-eye photoreceptor cell development-
GO:0045087IEA-innate immune response-
GO:0045165IEA-cell fate commitment-
GO:0045579IEA-positive regulation of B cell differentiation-
GO:0048844IEA-artery morphogenesis-
GO:0051136ISS-regulation of NK T cell differentiation-
GO:0060576IEA-intestinal epithelial cell development-
GO:0060707IEA-trophoblast giant cell differentiation-
GO:0060976IEA-coronary vasculature development-
GO:1990654IEA-sebum secreting cell proliferation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TLE1PRDM11129439887105 Reconstituted Complex
TLE1PRDM11071089887105 Reconstituted Complex
TLE2PRDM11129449887105 Reconstituted Complex
TLE2PRDM11071089887105 Reconstituted Complex
HDAC2PRDM110710810713181 12626569 19124609 Affinity Capture-Western; Reconstituted Complex
HDAC2PRDM110931610713181 12626569 19124609 Affinity Capture-Western; Reconstituted Complex
EHMT2PRDM111612314985713 19124609 Affinity Capture-Western
EHMT2PRDM110710814985713 19124609 Affinity Capture-Western
SUV39H1PRDM110710814985713 Affinity Capture-Western
SUV39H1PRDM111270614985713 Affinity Capture-Western
HIST2H3APRDM113061614985713 Biochemical Activity
HIST2H3APRDM110710814985713 Biochemical Activity
PRMT5PRDM110710816699504 18992153 Affinity Capture-Western
PRMT5PRDM111568816699504 18992153 Affinity Capture-Western
PRMT7PRDM111999218992153 Affinity Capture-Western
PRMT7PRDM110710818992153 Affinity Capture-Western
HDAC1PRDM110931519124609 Affinity Capture-Western
HDAC1PRDM110710819124609 Affinity Capture-Western
KDM1APRDM110710819124609 Affinity Capture-Western; Reconstituted Complex
KDM1APRDM111666719124609 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99655
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2193'