AutismKB 2.0

Annotation Details for ZNF335


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Basic Information Top
Gene Symbol:ZNF335 ( NIF-1,NIF1,NIF2 )
Gene Full Name: zinc finger protein 335
Band: 20q13.12
Quick LinksEntrez ID:63925; OMIM: 610827; Uniprot ID:ZN335_HUMAN; ENSEMBL ID: ENSG00000198026; HGNC ID: 15807
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634ISS-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0035097IDAcolocalizes_withhistone methyltransferase complex23178126
GO ID Evidence Qualifier GO_term References
GO:0000979IEA-RNA polymerase II core promoter sequence-specific DNA binding-
GO:0005515IPI-protein binding18180299
GO:0044212ISS-transcription regulatory region DNA binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001701IEA-in utero embryonic development-
GO:0002052ISS-positive regulation of neuroblast proliferation-
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0007420IMP-brain development23178126
GO:0021895IEA-cerebral cortex neuron differentiation-
GO:0040029IMP-regulation of gene expression, epigenetic23178126
GO:0048812ISS-neuron projection morphogenesis-
GO:0048854IEA-brain morphogenesis-
GO:0050671IMP-positive regulation of lymphocyte proliferation23178126
GO:0050769IMP-positive regulation of neurogenesis23178126
GO:0051569IEA-regulation of histone H3-K4 methylation-
GO:0080182IMP-histone H3-K4 trimethylation23178126
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZNF335HCFC110930419131338 Affinity Capture-Western
ZNF335HCFC112199419131338 Affinity Capture-Western
ZNF335RBBP511186419131338 Affinity Capture-Western
ZNF335RBBP512199419131338 Affinity Capture-Western
ZNF335ASH2L11452819131338 Affinity Capture-Western
ZNF335ASH2L12199419131338 Affinity Capture-Western
ZNF335WDR512199419131338 Affinity Capture-Western
ZNF335WDR511627219131338 Affinity Capture-Western
ZNF335NCOA612199412215545 Reconstituted Complex; Two-hybrid
ZNF335NCOA611669112215545 Reconstituted Complex; Two-hybrid
ZNF335C11orf3012127019131338 Affinity Capture-Western
ZNF335C11orf3012199419131338 Affinity Capture-Western
ZNF335KIAA196712199419131338 Affinity Capture-Western; Two-hybrid
ZNF335KIAA196712177519131338 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2682313
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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