AutismKB 2.0

Annotation Details for BLK


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Basic Information Top
Gene Symbol:BLK ( MGC10442,MODY11 )
Gene Full Name: B lymphoid tyrosine kinase
Band: 8p23.1
Quick LinksEntrez ID:640; OMIM: 191305; Uniprot ID:BLK_HUMAN; ENSEMBL ID: ENSG00000136573; HGNC ID: 1057
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0031234IBA-extrinsic component of cytoplasmic side of plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0004713TAS-protein tyrosine kinase activity7845672
GO:0004715IDA-non-membrane spanning protein tyrosine kinase activity876631
GO:0005102IBA-receptor binding-
GO:0005515IPI-protein binding16273093
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0007169IBA-transmembrane receptor protein tyrosine kinase signaling pathway-
GO:0016477IBA-cell migration-
GO:0030154IBA-cell differentiation-
GO:0032024IMP-positive regulation of insulin secretion19667185
GO:0035556TAS-intracellular signal transduction2404338
GO:0038083IBA-peptidyl-tyrosine autophosphorylation-
GO:0042127IBA-regulation of cell proliferation-
GO:0045087IBA-innate immune response-
GO:0050853IDA-B cell receptor signaling pathway876631
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BLKBCL21071099525867 Reconstituted Complex
BLKBCL21070689525867 Reconstituted Complex
BLKBCL2L11071099525867 Reconstituted Complex
BLKBCL2L11070709525867 Reconstituted Complex
CD79ABLK1071097592958 Affinity Capture-Western
CD79ABLK1074117592958 Affinity Capture-Western
CD79BBLK1071097592958 Affinity Capture-Western
CD79BBLK1074127592958 Affinity Capture-Western
PLCG2BLK1071098395016 Reconstituted Complex
PLCG2BLK1113528395016 Reconstituted Complex
UBE3ABLK10710910449731 Reconstituted Complex
UBE3ABLK11318510449731 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88169
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040724-106'