AutismKB 2.0

Annotation Details for SELP


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Basic Information Top
Gene Symbol:SELP ( CD62,CD62P,FLJ45155,GMP140,GRMP,LECAM3,PADGEM,PSEL )
Gene Full Name: selectin P (granule membrane protein 140kDa, antigen CD62)
Band: 1q24.2
Quick LinksEntrez ID:6403; OMIM: 173610; Uniprot ID:LYAM3_HUMAN; ENSEMBL ID: ENSG00000174175; HGNC ID: 10721
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space9290466
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane1701178
GO:0009897IDA-external side of plasma membrane16514062
GO:0031088TAS-platelet dense granule membrane-
GO:0031092IDA-platelet alpha granule membrane15297306
GO:0031092TAS-platelet alpha granule membrane-
GO ID Evidence Qualifier GO_term References
GO:0001530IMP-lipopolysaccharide binding16514062
GO:0001948IEA-glycoprotein binding-
GO:0005515IPI-protein binding9129046
GO:0008201IDA-heparin binding7680663
GO:0033691IDA-sialic acid binding7680663
GO:0042806IDA-fucose binding7680663
GO:0043208TAS-glycosphingolipid binding7680663
GO:0048306IEA-calcium-dependent protein binding-
GO:0070492IDA-oligosaccharide binding7680663
GO ID Evidence Qualifier GO_term References
GO:0002576TAS-platelet degranulation-
GO:0002687IEA-positive regulation of leukocyte migration-
GO:0006954IEA-inflammatory response-
GO:0007155TAS-cell adhesion2466574
GO:0007157IEA-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-
GO:0007159IDA-leukocyte cell-cell adhesion7680663
GO:0010572ISS-positive regulation of platelet activation16514062
GO:0014068IDA-positive regulation of phosphatidylinositol 3-kinase signaling17632516
GO:0032496IC-response to lipopolysaccharide16514062
GO:0033623IMP-regulation of integrin activation17632516
GO:0035584IGI-calcium-mediated signaling using intracellular calcium source15879141
GO:0050829IC-defense response to Gram-negative bacterium16514062
GO:0050900TAS-leukocyte migration-
GO:0050901IEA-leukocyte tethering or rolling-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SELPSERPING111230314568956 Affinity Capture-Western
SELPSERPING110717114568956 Affinity Capture-Western
SELPVCAN11230310950950 Reconstituted Complex
SELPVCAN10784410950950 Reconstituted Complex
SELPGP1BA10907310499919 Reconstituted Complex
SELPGP1BA11230310499919 Reconstituted Complex
CD24SELP1073729129046 Reconstituted Complex
CD24SELP1123039129046 Reconstituted Complex
SELPLGSELP11230310713099 Affinity Capture-Western
SELPLGSELP11230410713099 Affinity Capture-Western
EZRSELP11230310733515 Reconstituted Complex
EZRSELP11327110733515 Reconstituted Complex
SNX17SELP11512811237770 Two-hybrid
SNX17SELP11230311237770 Two-hybrid
AP1M1SELP11442111247301 Co-crystal Structure
AP1M1SELP11230311247301 Co-crystal Structure
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98280
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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