Gene Symbol:	IFIH1 ( Hlcd,IDDM19,MDA-5,MDA5,MGC133047 )
Gene Full Name:	interferon induced with helicase C domain 1
Band:	2q24.2
Quick Links	Entrez ID:64135; OMIM: 606951; Uniprot ID:IFIH1_HUMAN; ENSEMBL ID: ENSG00000115267; HGNC ID: 18873
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0003677	IEA	-	DNA binding	-
GO:0003725	IDA	-	double-stranded RNA binding	19656871
GO:0003725	TAS	-	double-stranded RNA binding	17079289
GO:0003727	IDA	-	single-stranded RNA binding	19656871
GO:0004386	IEA	-	helicase activity	-
GO:0005515	IPI	-	protein binding	16127453
GO:0005524	IEA	-	ATP binding	-
GO:0008270	IDA	-	zinc ion binding	19380577
GO:0042802	IPI	-	identical protein binding	25865883
GO:0043021	IPI	-	ribonucleoprotein complex binding	19881509

GO ID	Evidence	Qualifier	GO_term	References
GO:0009597	TAS	-	detection of virus	17079289
GO:0009615	TAS	-	response to virus	21616437
GO:0016579	TAS	-	protein deubiquitination	-
GO:0016925	IDA	-	protein sumoylation	21156324
GO:0032480	TAS	-	negative regulation of type I interferon production	-
GO:0032727	IMP	-	positive regulation of interferon-alpha production	19656871
GO:0032727	TAS	-	positive regulation of interferon-alpha production	17079289
GO:0032728	IDA	-	positive regulation of interferon-beta production	17600090
GO:0032728	IMP	-	positive regulation of interferon-beta production	19211564
GO:0032728	TAS	-	positive regulation of interferon-beta production	17079289
GO:0034344	TAS	-	regulation of type III interferon production	21616437
GO:0039528	TAS	-	cytoplasmic pattern recognition receptor signaling pathway in response to virus	21616437
GO:0039530	IDA	-	MDA-5 signaling pathway	17600090
GO:0045087	TAS	-	innate immune response	21616437

AutismKB 2.0

Annotation Details for IFIH1