AutismKB 2.0

Annotation Details for SET


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Basic Information Top
Gene Symbol:SET ( 2PP2A,I2PP2A,IGAAD,IPP2A2,PHAPII,TAF-I,TAF-IBETA )
Gene Full Name: SET nuclear oncogene
Band: 9q34.11
Quick LinksEntrez ID:6418; OMIM: 600960; Uniprot ID:SET_HUMAN; ENSEMBL ID: ENSG00000119335; HGNC ID: 10760
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus11555662
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm11909973
GO:0005783IDA-endoplasmic reticulum11555662
GO:0005811IDA-lipid particle-
GO:0005829IEA-cytosol-
GO:0043234IDA-protein complex11909973
GO:0048471IDA-perinuclear region of cytoplasm11555662
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0004864TAS-protein phosphatase inhibitor activity8626647
GO:0005515IPI-protein binding11909973
GO:0019888TAS-protein phosphatase regulator activity11555662
GO:0042393TAS-histone binding11555662
GO ID Evidence Qualifier GO_term References
GO:0006260TAS-DNA replication7753797
GO:0006334IEA-nucleosome assembly-
GO:0006337TAS-nucleosome disassembly11555662
GO:0006913NAS-nucleocytoplasmic transport11555662
GO:0016032IEA-viral process-
GO:0035067TAS-negative regulation of histone acetylation11555662
GO:0043086IEA-negative regulation of catalytic activity-
GO:0043488TAS-regulation of mRNA stability-
GO:0043524IGI-negative regulation of neuron apoptotic process18374643
GO:0045892IDA-negative regulation of transcription, DNA-templated19343227
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SETAPBB110681915592452 Affinity Capture-MS; Affinity Capture-Western
SETAPBB111231615592452 Affinity Capture-MS; Affinity Capture-Western
SETAPEX110682512524539 Affinity Capture-Western
SETAPEX111231612524539 Affinity Capture-Western
SETAPP10684816162853 Protein-peptide
SETAPP11231616162853 Protein-peptide
SETKLF510715314612398 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SETKLF511231614612398 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SETCCNB110733216474839 Affinity Capture-Western
SETCCNB111231616474839 Affinity Capture-Western
SETCDKN1A10746012407107 16474839 Reconstituted Complex
SETCDKN1A11231612407107 16474839 Reconstituted Complex
SETCHRM210755117065150 Reconstituted Complex
SETCHRM211231617065150 Reconstituted Complex
SETCHRM310755317065150 Affinity Capture-Western; Reconstituted Complex
SETCHRM311231617065150 Affinity Capture-Western; Reconstituted Complex
SETGAPDH10886816474839 Affinity Capture-Western; Reconstituted Complex
SETGAPDH11231616474839 Affinity Capture-Western; Reconstituted Complex
SETNR3C110916518096310 Affinity Capture-Western; Two-hybrid
SETNR3C111231618096310 Affinity Capture-Western; Two-hybrid
SETGZMA10925611555662 Reconstituted Complex
SETGZMA11231611555662 Reconstituted Complex
SETHMGB210939111909973 Reconstituted Complex
SETHMGB211231611909973 Reconstituted Complex
SETMGMT11041116226712 Affinity Capture-MS
SETMGMT11231616226712 Affinity Capture-MS
SETMLL1104439353299 Reconstituted Complex; Two-hybrid
SETMLL1123169353299 Reconstituted Complex; Two-hybrid
SETNME111089412628186 Affinity Capture-Western
SETNME111231612628186 Affinity Capture-Western
SETNUP8811098115239126 Affinity Capture-Western
SETNUP8811231615239126 Affinity Capture-Western
SETPTMA11172415556635 Affinity Capture-MS; Affinity Capture-Western
SETPTMA11231615556635 Affinity Capture-MS; Affinity Capture-Western
SETSET11231610390352 10490631 Co-purification; Reconstituted Complex
ANP32ASET11379111163245 11909973 17142970 Affinity Capture-Western; Co-purification; Reconstituted Complex
ANP32ASET11231611163245 11909973 17142970 Affinity Capture-Western; Co-purification; Reconstituted Complex
TAF1ASET11448411163245 Co-purification; Reconstituted Complex
TAF1ASET11231611163245 Co-purification; Reconstituted Complex
HIST4H4SET12573211163245 Reconstituted Complex
HIST4H4SET11231611163245 Reconstituted Complex
HIST3H3SET11389511163245 Reconstituted Complex
HIST3H3SET11231611163245 Reconstituted Complex
SETBP1SET11750611231286 Affinity Capture-Western; Two-hybrid
SETBP1SET11231611231286 Affinity Capture-Western; Two-hybrid
CDK5R1SET11437611741927 Affinity Capture-Western; Reconstituted Complex
CDK5R1SET11231611741927 Affinity Capture-Western; Reconstituted Complex
HIST1H3ASET11394615100215 19358706 Affinity Capture-Western; Protein-peptide; Reconstituted Complex
HIST1H3ASET11231615100215 19358706 Affinity Capture-Western; Protein-peptide; Reconstituted Complex
XPO1SET11334815239126 Affinity Capture-Western
XPO1SET11231615239126 Affinity Capture-Western
THAP7SET12329816189514 Two-hybrid
THAP7SET11231616189514 Two-hybrid
TREX1SET11643316818237 Co-purification; Reconstituted Complex
TREX1SET11231616818237 Co-purification; Reconstituted Complex
DGKESET11409617353931 Affinity Capture-MS
DGKESET11231617353931 Affinity Capture-MS
RGS20SET11416117353931 Affinity Capture-MS
RGS20SET11231617353931 Affinity Capture-MS
MEPCESET12112217643375 Affinity Capture-MS
MEPCESET11231617643375 Affinity Capture-MS
HIST1H2BASET12911119358706 Reconstituted Complex
HIST1H2BASET11231619358706 Reconstituted Complex
USP17L2SET13201919615732 Affinity Capture-MS
USP17L2SET11231619615732 Affinity Capture-MS
OTUD5SET12073819615732 Affinity Capture-MS
OTUD5SET11231619615732 Affinity Capture-MS
WDR48SET12164919615732 Affinity Capture-MS
WDR48SET11231619615732 Affinity Capture-MS
USP46SET12232719615732 Affinity Capture-MS
USP46SET11231619615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1860267
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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