AutismKB 2.0

Annotation Details for SFPQ


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SFPQ ( POMP100,PSF )
Gene Full Name: splicing factor proline/glutamine-rich
Band: 1p34.3
Quick LinksEntrez ID:6421; OMIM: 605199; Uniprot ID:SFPQ_HUMAN; ENSEMBL ID: ENSG00000116560; HGNC ID: 10774
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000785IDA-chromatin16731528
GO:0005634IDA-nucleus15790595
GO:0005654IDA-nucleoplasm19874820
GO:0005654TAS-nucleoplasm-
GO:0005737IEA-cytoplasm-
GO:0016363IDA-nuclear matrix19874820
GO:0016607IEA-nuclear speck-
GO:0031012IDA-extracellular matrix23979707
GO:0042382IDA-paraspeckles19874820
GO:0090575ISS-RNA polymerase II transcription factor complex-
GO ID Evidence Qualifier GO_term References
GO:0000976IBA-transcription regulatory region sequence-specific DNA binding-
GO:0000976ISS-transcription regulatory region sequence-specific DNA binding-
GO:0000980ISS-RNA polymerase II distal enhancer sequence-specific DNA binding-
GO:0001047ISS-core promoter binding-
GO:0003677IDA-DNA binding25765647
GO:0003682ISS-chromatin binding-
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding9848648
GO:0042803IPI-protein homodimerization activity25765647
GO:0042826IPI-histone deacetylase binding16731528
GO:0044212IDA-transcription regulatory region DNA binding16731528
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter16731528
GO:0000122IGI-negative regulation of transcription from RNA polymerase II promoter15790595
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter22783022
GO:0000380IMP-alternative mRNA splicing, via spliceosome19874820
GO:0000724IMP-double-strand break repair via homologous recombination20813759
GO:0006351IEA-transcription, DNA-templated-
GO:0006397TAS-mRNA processing8449401
GO:0008380TAS-RNA splicing8449401
GO:0042752ISS-regulation of circadian rhythm-
GO:0042754ISS-negative regulation of circadian rhythm-
GO:0045876IEA-positive regulation of sister chromatid cohesion-
GO:0045892ISS-negative regulation of transcription, DNA-templated-
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter25765647
GO:0048511IEA-rhythmic process-
GO:0070932ISS-histone H3 deacetylation-
GO:1902177IDA-positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway15790595
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SFPQAPBB110681916055720 Affinity Capture-MS
SFPQAPBB111231916055720 Affinity Capture-MS
SFPQAR11231917452459 Affinity Capture-Western; Reconstituted Complex
SFPQAR10686217452459 Affinity Capture-Western; Reconstituted Complex
SFPQCDC5L11231911101529 Affinity Capture-MS; Co-purification
SFPQCDC5L10742411101529 Affinity Capture-MS; Co-purification
SFPQFHL210856511161712 Two-hybrid
SFPQFHL211231911161712 Two-hybrid
SFPQNR3C110916519339282 Affinity Capture-Western
SFPQNR3C111231919339282 Affinity Capture-Western
SFPQHDAC110931519339282 Affinity Capture-Western
SFPQHDAC111231919339282 Affinity Capture-Western
SFPQHDAC210931619339282 Affinity Capture-Western
SFPQHDAC211231919339282 Affinity Capture-Western
SFPQNONO11090412403470 17452459 18042045 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SFPQNONO11231912403470 17452459 18042045 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SFPQNR4A211098319144721 Affinity Capture-Western
SFPQNR4A211231919144721 Affinity Capture-Western
SFPQPIN111231916055720 Affinity Capture-MS
SFPQPIN111131716055720 Affinity Capture-MS
SFPQPITX311231919144721 Affinity Capture-MS; Affinity Capture-Western
SFPQPITX311132619144721 Affinity Capture-MS; Affinity Capture-Western
SFPQPTBP11123198449401 10653975 Affinity Capture-Western; Reconstituted Complex
SFPQPTBP11116978449401 10653975 Affinity Capture-Western; Reconstituted Complex
SFPQRAC111231920936779 Two-hybrid
SFPQRAC111181720936779 Two-hybrid
TOP1SFPQ1130039756848 Affinity Capture-Western
TOP1SFPQ1123199756848 Affinity Capture-Western
EXOSC5SFPQ12124315231747 Two-hybrid
EXOSC5SFPQ11231915231747 Two-hybrid
ZMYM2SFPQ11353415975576 Affinity Capture-MS; Affinity Capture-Western
ZMYM2SFPQ11231915975576 Affinity Capture-MS; Affinity Capture-Western
TCERG1SFPQ11612016055720 Affinity Capture-MS
TCERG1SFPQ11231916055720 Affinity Capture-MS
WBP4SFPQ11636316055720 Affinity Capture-MS
WBP4SFPQ11231916055720 Affinity Capture-MS
WWOXSFPQ11231916055720 Affinity Capture-MS
WWOXSFPQ11970716055720 Affinity Capture-MS
PRPF40ASFPQ11231916055720 Affinity Capture-MS
PRPF40ASFPQ12079216055720 Affinity Capture-MS
GAS7SFPQ11409416055720 Affinity Capture-MS
GAS7SFPQ11231916055720 Affinity Capture-MS
SRRM1SFPQ11231916159877 Affinity Capture-MS
SRRM1SFPQ11554416159877 Affinity Capture-MS
SRRM2SFPQ11707116159877 Affinity Capture-MS
SRRM2SFPQ11231916159877 Affinity Capture-MS
HN1SFPQ11933816169070 Two-hybrid
HN1SFPQ11231916169070 Two-hybrid
SFPQSFPQ11231916169070 Two-hybrid
UBCSFPQ11316416169070 Two-hybrid
UBCSFPQ11231916169070 Two-hybrid
SIN3ASFPQ11743917452459 19339282 Affinity Capture-Western; Co-localization
SIN3ASFPQ11231917452459 19339282 Affinity Capture-Western; Co-localization
TOPORSSFPQ11550517803295 Affinity Capture-MS
TOPORSSFPQ11231917803295 Affinity Capture-MS
SMARCA2SFPQ11231918042045 Affinity Capture-Western
SMARCA2SFPQ11247918042045 Affinity Capture-Western
SMARCD1SFPQ11231918042045 Affinity Capture-Western
SMARCD1SFPQ11248618042045 Affinity Capture-Western
SP1SFPQ11231919339282 Affinity Capture-Western
SP1SFPQ11255019339282 Affinity Capture-Western
SP3SFPQ11255319339282 Affinity Capture-Western
SP3SFPQ11231919339282 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1918764
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2452'