Gene Symbol:	SFPQ ( POMP100,PSF )
Gene Full Name:	splicing factor proline/glutamine-rich
Band:	1p34.3
Quick Links	Entrez ID:6421; OMIM: 605199; Uniprot ID:SFPQ_HUMAN; ENSEMBL ID: ENSG00000116560; HGNC ID: 10774
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0000785	IDA	-	chromatin	16731528
GO:0005634	IDA	-	nucleus	15790595
GO:0005654	IDA	-	nucleoplasm	19874820
GO:0005654	TAS	-	nucleoplasm	-
GO:0005737	IEA	-	cytoplasm	-
GO:0016363	IDA	-	nuclear matrix	19874820
GO:0016607	IEA	-	nuclear speck	-
GO:0031012	IDA	-	extracellular matrix	23979707
GO:0042382	IDA	-	paraspeckles	19874820
GO:0090575	ISS	-	RNA polymerase II transcription factor complex	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000976	IBA	-	transcription regulatory region sequence-specific DNA binding	-
GO:0000976	ISS	-	transcription regulatory region sequence-specific DNA binding	-
GO:0000980	ISS	-	RNA polymerase II distal enhancer sequence-specific DNA binding	-
GO:0001047	ISS	-	core promoter binding	-
GO:0003677	IDA	-	DNA binding	25765647
GO:0003682	ISS	-	chromatin binding	-
GO:0003723	IDA	-	RNA binding	22658674
GO:0005515	IPI	-	protein binding	9848648
GO:0042803	IPI	-	protein homodimerization activity	25765647
GO:0042826	IPI	-	histone deacetylase binding	16731528
GO:0044212	IDA	-	transcription regulatory region DNA binding	16731528

GO ID	Evidence	Qualifier	GO_term	References
GO:0000122	IDA	-	negative regulation of transcription from RNA polymerase II promoter	16731528
GO:0000122	IGI	-	negative regulation of transcription from RNA polymerase II promoter	15790595
GO:0000122	IMP	-	negative regulation of transcription from RNA polymerase II promoter	22783022
GO:0000380	IMP	-	alternative mRNA splicing, via spliceosome	19874820
GO:0000724	IMP	-	double-strand break repair via homologous recombination	20813759
GO:0006351	IEA	-	transcription, DNA-templated	-
GO:0006397	TAS	-	mRNA processing	8449401
GO:0008380	TAS	-	RNA splicing	8449401
GO:0042752	ISS	-	regulation of circadian rhythm	-
GO:0042754	ISS	-	negative regulation of circadian rhythm	-
GO:0045876	IEA	-	positive regulation of sister chromatid cohesion	-
GO:0045892	ISS	-	negative regulation of transcription, DNA-templated	-
GO:0045944	IMP	-	positive regulation of transcription from RNA polymerase II promoter	25765647
GO:0048511	IEA	-	rhythmic process	-
GO:0070932	ISS	-	histone H3 deacetylation	-
GO:1902177	IDA	-	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	15790595

Gene Symbol	Interactant	Interaction ID	References	Description
SFPQ	APBB1	106819	16055720	Affinity Capture-MS
SFPQ	APBB1	112319	16055720	Affinity Capture-MS
SFPQ	AR	112319	17452459	Affinity Capture-Western; Reconstituted Complex
SFPQ	AR	106862	17452459	Affinity Capture-Western; Reconstituted Complex
SFPQ	CDC5L	112319	11101529	Affinity Capture-MS; Co-purification
SFPQ	CDC5L	107424	11101529	Affinity Capture-MS; Co-purification
SFPQ	FHL2	108565	11161712	Two-hybrid
SFPQ	FHL2	112319	11161712	Two-hybrid
SFPQ	NR3C1	109165	19339282	Affinity Capture-Western
SFPQ	NR3C1	112319	19339282	Affinity Capture-Western
SFPQ	HDAC1	109315	19339282	Affinity Capture-Western
SFPQ	HDAC1	112319	19339282	Affinity Capture-Western
SFPQ	HDAC2	109316	19339282	Affinity Capture-Western
SFPQ	HDAC2	112319	19339282	Affinity Capture-Western
SFPQ	NONO	110904	12403470 17452459 18042045	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SFPQ	NONO	112319	12403470 17452459 18042045	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SFPQ	NR4A2	110983	19144721	Affinity Capture-Western
SFPQ	NR4A2	112319	19144721	Affinity Capture-Western
SFPQ	PIN1	112319	16055720	Affinity Capture-MS
SFPQ	PIN1	111317	16055720	Affinity Capture-MS
SFPQ	PITX3	112319	19144721	Affinity Capture-MS; Affinity Capture-Western
SFPQ	PITX3	111326	19144721	Affinity Capture-MS; Affinity Capture-Western
SFPQ	PTBP1	112319	8449401 10653975	Affinity Capture-Western; Reconstituted Complex
SFPQ	PTBP1	111697	8449401 10653975	Affinity Capture-Western; Reconstituted Complex
SFPQ	RAC1	112319	20936779	Two-hybrid
SFPQ	RAC1	111817	20936779	Two-hybrid
TOP1	SFPQ	113003	9756848	Affinity Capture-Western
TOP1	SFPQ	112319	9756848	Affinity Capture-Western
EXOSC5	SFPQ	121243	15231747	Two-hybrid
EXOSC5	SFPQ	112319	15231747	Two-hybrid
ZMYM2	SFPQ	113534	15975576	Affinity Capture-MS; Affinity Capture-Western
ZMYM2	SFPQ	112319	15975576	Affinity Capture-MS; Affinity Capture-Western
TCERG1	SFPQ	116120	16055720	Affinity Capture-MS
TCERG1	SFPQ	112319	16055720	Affinity Capture-MS
WBP4	SFPQ	116363	16055720	Affinity Capture-MS
WBP4	SFPQ	112319	16055720	Affinity Capture-MS
WWOX	SFPQ	112319	16055720	Affinity Capture-MS
WWOX	SFPQ	119707	16055720	Affinity Capture-MS
PRPF40A	SFPQ	112319	16055720	Affinity Capture-MS
PRPF40A	SFPQ	120792	16055720	Affinity Capture-MS
GAS7	SFPQ	114094	16055720	Affinity Capture-MS
GAS7	SFPQ	112319	16055720	Affinity Capture-MS
SRRM1	SFPQ	112319	16159877	Affinity Capture-MS
SRRM1	SFPQ	115544	16159877	Affinity Capture-MS
SRRM2	SFPQ	117071	16159877	Affinity Capture-MS
SRRM2	SFPQ	112319	16159877	Affinity Capture-MS
HN1	SFPQ	119338	16169070	Two-hybrid
HN1	SFPQ	112319	16169070	Two-hybrid
SFPQ	SFPQ	112319	16169070	Two-hybrid
UBC	SFPQ	113164	16169070	Two-hybrid
UBC	SFPQ	112319	16169070	Two-hybrid
SIN3A	SFPQ	117439	17452459 19339282	Affinity Capture-Western; Co-localization
SIN3A	SFPQ	112319	17452459 19339282	Affinity Capture-Western; Co-localization
TOPORS	SFPQ	115505	17803295	Affinity Capture-MS
TOPORS	SFPQ	112319	17803295	Affinity Capture-MS
SMARCA2	SFPQ	112319	18042045	Affinity Capture-Western
SMARCA2	SFPQ	112479	18042045	Affinity Capture-Western
SMARCD1	SFPQ	112319	18042045	Affinity Capture-Western
SMARCD1	SFPQ	112486	18042045	Affinity Capture-Western
SP1	SFPQ	112319	19339282	Affinity Capture-Western
SP1	SFPQ	112550	19339282	Affinity Capture-Western
SP3	SFPQ	112553	19339282	Affinity Capture-Western
SP3	SFPQ	112319	19339282	Affinity Capture-Western

AutismKB 2.0

Annotation Details for SFPQ