AutismKB 2.0

Annotation Details for MLST8


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Basic Information Top
Gene Symbol:MLST8 ( GBL,GbetaL,LST8,MGC111011,POP3,WAT1 )
Gene Full Name: MTOR associated protein, LST8 homolog (S. cerevisiae)
Band: 16p13.3
Quick LinksEntrez ID:64223; OMIM: 612190; Uniprot ID:LST8_HUMAN; ENSEMBL ID: ENSG00000167965; HGNC ID: 24825
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0005737ISS-cytoplasm-
GO:0005829TAS-cytosol-
GO:0031931IDA-TORC1 complex12718876
GO:0031932IDA-TORC2 complex24036451
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding12408816
GO:0043539IDA-protein serine/threonine kinase activator activity12718876
GO ID Evidence Qualifier GO_term References
GO:0007050TAS-cell cycle arrest-
GO:0016241TAS-regulation of macroautophagy-
GO:0030838IEA-positive regulation of actin filament polymerization-
GO:0031295TAS-T cell costimulation-
GO:0032008IMP-positive regulation of TOR signaling15467718
GO:0032956IMP-regulation of actin cytoskeleton organization15467718
GO:0038202IMP-TORC1 signaling12718876
GO:0043087IEA-regulation of GTPase activity-
GO:0048015TAS-phosphatidylinositol-mediated signaling-
GO:0050731IEA-positive regulation of peptidyl-tyrosine phosphorylation-
GO:0071902IEA-positive regulation of protein serine/threonine kinase activity-
GO:1900034TAS-regulation of cellular response to heat-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MLST8MTOR10875712719976 15066126 16183647 20427287 20562859 Affinity Capture-MS; Affinity Capture-Western
MLST8MTOR12211312719976 15066126 16183647 20427287 20562859 Affinity Capture-MS; Affinity Capture-Western
MLST8KRT8512211320562859 Affinity Capture-MS
MLST8KRT8511008920562859 Affinity Capture-MS
MLST8CCT212211320562859 Affinity Capture-MS
MLST8CCT211582720562859 Affinity Capture-MS
MLST8RPTOR12158220562859 Affinity Capture-MS
MLST8RPTOR12211320562859 Affinity Capture-MS
No data
Gene Symbol Interactant Interaction ID References Description
MLST8RPTOR1703112718876 -
MLST8RPTOR0618412718876 -
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1929514
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6176'