AutismKB 2.0

Annotation Details for SRSF6


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Basic Information Top
Gene Symbol:SRSF6 ( B52,FLJ08061,MGC5045,SFRS6,SRP55 )
Gene Full Name: serine/arginine-rich splicing factor 6
Band: 20q13.11
Quick LinksEntrez ID:6431; OMIM: 601944; Uniprot ID:SRSF6_HUMAN; ENSEMBL ID: ENSG00000124193; HGNC ID: 10788
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0016607IDA-nuclear speck22767602
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding25416956
GO:0036002IDA-pre-mRNA binding12549914
GO ID Evidence Qualifier GO_term References
GO:0000380IDA-alternative mRNA splicing, via spliceosome22767602
GO:0000381IDA-regulation of alternative mRNA splicing, via spliceosome23132731
GO:0000381IMP-regulation of alternative mRNA splicing, via spliceosome24440982
GO:0000398TAS-mRNA splicing, via spliceosome-
GO:0006369TAS-termination of RNA polymerase II transcription-
GO:0006376IMP-mRNA splice site selection12549914
GO:0006405TAS-RNA export from nucleus-
GO:0006406TAS-mRNA export from nucleus-
GO:0010837IMP-regulation of keratinocyte proliferation24440982
GO:0031124TAS-mRNA 3'-end processing-
GO:0032868IEA-response to insulin-
GO:0045617IMP-negative regulation of keratinocyte differentiation24440982
GO:0048025IDA-negative regulation of mRNA splicing, via spliceosome15009664
GO:0060501IDA-positive regulation of epithelial cell proliferation involved in lung morphogenesis23132731
GO:0060548IDA-negative regulation of cell death23132731
GO:0061041IMP-regulation of wound healing24440982
GO:2000675IEA-negative regulation of type B pancreatic cell apoptotic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SRSF6SRSF411232716189514 Two-hybrid
SRSF6SRSF411232916189514 Two-hybrid
SRPK2SRSF61123299472028 Biochemical Activity
SRPK2SRSF61126119472028 Biochemical Activity
PPARGC1ASRSF611232910983978 Affinity Capture-Western
PPARGC1ASRSF611609710983978 Affinity Capture-Western
SRRM1SRSF611554416159877 Co-fractionation
SRRM1SRSF611232916159877 Co-fractionation
RNPS1SRSF611232916189514 Two-hybrid
RNPS1SRSF611612516189514 Two-hybrid
YWHAQSRSF611616817353931 Affinity Capture-MS
YWHAQSRSF611232917353931 Affinity Capture-MS
RRP1BSRSF611232919710015 Affinity Capture-MS
RRP1BSRSF611670819710015 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1915246
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2824'