AutismKB 2.0

Annotation Details for SFTPD


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Basic Information Top
Gene Symbol:SFTPD ( COLEC7,PSP-D,SFTP4,SP-D )
Gene Full Name: surfactant protein D
Band: 10q22.3
Quick LinksEntrez ID:6441; OMIM: 178635; Uniprot ID:SFTPD_HUMAN; ENSEMBL ID: ENSG00000133661; HGNC ID: 10803
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region9751757
GO:0005578IEA-proteinaceous extracellular matrix-
GO:0005581IEA-collagen trimer-
GO:0005615IEA-extracellular space-
GO:0005764TAS-lysosome10485905
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0030139TAS-endocytic vesicle10485905
GO:0042599TAS-lamellar body-
GO:0045334TAS-clathrin-coated endocytic vesicle-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding12884308
GO:0030246TAS-carbohydrate binding10485905
GO ID Evidence Qualifier GO_term References
GO:0001817NAS-regulation of cytokine production9751757
GO:0002224TAS-toll-like receptor signaling pathway-
GO:0006898TAS-receptor-mediated endocytosis10485905
GO:0007585IEA-respiratory gaseous exchange-
GO:0042130TAS-negative regulation of T cell proliferation10485905
GO:0042742TAS-defense response to bacterium9751757
GO:0043129IMP-surfactant homeostasis9751757
GO:0044267TAS-cellular protein metabolic process-
GO:0045085TAS-negative regulation of interleukin-2 biosynthetic process10485905
GO:0045087TAS-innate immune response10485905
GO:0048246TAS-macrophage chemotaxis10485905
GO:0048286IMP-lung alveolus development9751757
GO:0050766TAS-positive regulation of phagocytosis10485905
GO:0050776TAS-regulation of immune response-
GO:0072593TAS-reactive oxygen species metabolic process10485905
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SFTPDDCN11233912730206 Reconstituted Complex
SFTPDDCN10800212730206 Reconstituted Complex
SFTPDDMBT11080959153228 10101009 Co-purification; Reconstituted Complex
SFTPDDMBT11123399153228 10101009 Co-purification; Reconstituted Complex
SFTPA1SFTPD11233910101009 Co-purification
SFTPA1SFTPD57583910101009 Co-purification
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109515
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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