AutismKB 2.0

Annotation Details for SGK1


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Basic Information Top
Gene Symbol:SGK1 ( SGK )
Gene Full Name: serum/glucocorticoid regulated kinase 1
Band: 6q23.2
Quick LinksEntrez ID:6446; OMIM: 602958; Uniprot ID:SGK1_HUMAN; ENSEMBL ID: ENSG00000118515; HGNC ID: 10810
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005737IBA-cytoplasm-
GO:0005739IEA-mitochondrion-
GO:0005789IEA-endoplasmic reticulum membrane-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886IEA-plasma membrane-
GO:0016607IDA-nuclear speck-
GO ID Evidence Qualifier GO_term References
GO:0004674IBA-protein serine/threonine kinase activity-
GO:0004674TAS-protein serine/threonine kinase activity-
GO:0004712IDA-protein serine/threonine/tyrosine kinase activity22797923
GO:0005246TAS-calcium channel regulator activity20530112
GO:0005515IPI-protein binding20237237
GO:0005524IEA-ATP binding-
GO:0015459TAS-potassium channel regulator activity20530112
GO:0017080TAS-sodium channel regulator activity20530112
GO:0017081TAS-chloride channel regulator activity20530112
GO ID Evidence Qualifier GO_term References
GO:0001558TAS-regulation of cell growth20919962
GO:0006468TAS-protein phosphorylation9114008
GO:0006814TAS-sodium ion transport10884438
GO:0006915IEA-apoptotic process-
GO:0006950TAS-response to stress9114008
GO:0006974IEA-cellular response to DNA damage stimulus-
GO:0007616TAS-long-term memory20530112
GO:0008217TAS-regulation of blood pressure16460280
GO:0018105IBA-peptidyl-serine phosphorylation-
GO:0030334TAS-regulation of cell migration20919962
GO:0032411TAS-positive regulation of transporter activity20530112
GO:0034220TAS-ion transmembrane transport-
GO:0035556IBA-intracellular signal transduction-
GO:0042127TAS-regulation of cell proliferation20530112
GO:0042981TAS-regulation of apoptotic process20530112
GO:0048812IBA-neuron projection morphogenesis-
GO:0050790TAS-regulation of catalytic activity20530112
GO:0051090TAS-regulation of sequence-specific DNA binding transcription factor activity20530112
GO:0060453TAS-regulation of gastric acid secretion20530112
GO:0070294TAS-renal sodium ion absorption16460280
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SGK1CD4011234417353931 Affinity Capture-MS
SGK1CD4010739617353931 Affinity Capture-MS
SGK1FANCA10847214499622 Two-hybrid
SGK1FANCA11234414499622 Two-hybrid
SGK1IARS11234417353931 Affinity Capture-MS
SGK1IARS10960517353931 Affinity Capture-MS
SGK1IGHA111234417353931 Affinity Capture-MS
SGK1IGHA110971417353931 Affinity Capture-MS
SGK1KPNA211234412631736 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SGK1KPNA211003612631736 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SGK1LTF11234417353931 Affinity Capture-MS
SGK1LTF11023517353931 Affinity Capture-MS
SGK1MLLT311234417332896 Biochemical Activity
SGK1MLLT311044617332896 Biochemical Activity
SGK1NEDD411234411696533 12729930 Reconstituted Complex
SGK1NEDD411081111696533 12729930 Reconstituted Complex
SGK1PA2G411234417353931 Affinity Capture-MS
SGK1PA2G411107517353931 Affinity Capture-MS
SGK1PDPK111234410357815 12387817 Reconstituted Complex
SGK1PDPK111119610357815 12387817 Reconstituted Complex
SGK1PIGR11130217353931 Affinity Capture-MS
SGK1PIGR11234417353931 Affinity Capture-MS
SGK1PIK3CA11234410357815 Reconstituted Complex
SGK1PIK3CA11130810357815 Reconstituted Complex
SGK1PPP2CA11150710357815 Reconstituted Complex
SGK1PPP2CA11234410357815 Reconstituted Complex
SGK1MAPK711158411254654 Biochemical Activity; Reconstituted Complex; Two-hybrid
SGK1MAPK711234411254654 Biochemical Activity; Reconstituted Complex; Two-hybrid
SLC9A3R2SGK111475411751930 12387817 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SLC9A3R2SGK111234411751930 12387817 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CAMKK2SGK111588912628440 Affinity Capture-Western
CAMKK2SGK111234412628440 Affinity Capture-Western
UBCSGK111316415576372 Affinity Capture-Western
UBCSGK111234415576372 Affinity Capture-Western
CARHSP1SGK111712415910284 Reconstituted Complex
CARHSP1SGK111234415910284 Reconstituted Complex
CDC37SGK111631217353931 Affinity Capture-MS
CDC37SGK111234417353931 Affinity Capture-MS
TUFMSGK111313517353931 Affinity Capture-MS
TUFMSGK111234417353931 Affinity Capture-MS
VCPSGK111325817353931 Affinity Capture-MS
VCPSGK111234417353931 Affinity Capture-MS
IKBKGSGK111408920098747 Reconstituted Complex
IKBKGSGK111234420098747 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1340062
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2860'