AutismKB 2.0

Annotation Details for PLEKHG2


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Basic Information Top
Gene Symbol:PLEKHG2 ( ARHGEF42,CLG,DKFZp667J2325,FLJ00018,FLJ22458,FLJ38638 )
Gene Full Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Band: 19q13.2
Quick LinksEntrez ID:64857; OMIM: 611893; Uniprot ID:PKHG2_HUMAN; ENSEMBL ID: ENSG00000090924; HGNC ID: 29515
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0005085TAS-guanyl-nucleotide exchange factor activity-
GO:0005089TAS-Rho guanyl-nucleotide exchange factor activity-
GO ID Evidence Qualifier GO_term References
GO:0030833IMP-regulation of actin filament polymerization26573021
GO:0035023IEA-regulation of Rho protein signal transduction-
GO:0043065TAS-positive regulation of apoptotic process-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLEKHG2RHOA12233011839748 Reconstituted Complex
PLEKHG2RHOA10688011839748 Reconstituted Complex
PLEKHG2CDC4212233011839748 Reconstituted Complex
PLEKHG2CDC4210743311839748 Reconstituted Complex
PLEKHG2RAC112233011839748 Reconstituted Complex
PLEKHG2RAC111181711839748 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2141874
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-090819-1'