AutismKB 2.0

Annotation Details for SKI


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Basic Information Top
Gene Symbol:SKI ( SKV )
Gene Full Name: v-ski sarcoma viral oncogene homolog (avian)
Band: 1p36.33-p36.32
Quick LinksEntrez ID:6497; OMIM: 164780; Uniprot ID:SKI_HUMAN; ENSEMBL ID: ENSG00000157933; HGNC ID: 10896
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus17054724
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005667ISS-transcription factor complex-
GO:0005737ISS-cytoplasm-
GO:0005813IDA-centrosome21600873
GO:0016604IDA-nuclear body12874272
GO:0016605IDA-PML body11430826
GO:0017053ISS-transcriptional repressor complex-
GO:0043234IDA-protein complex23610558
GO ID Evidence Qualifier GO_term References
GO:0003714IDA-transcription corepressor activity17469184
GO:0003714IMP-transcription corepressor activity12435627
GO:0005515IPI-protein binding8514802
GO:0008270IDA-zinc ion binding12419246
GO:0019901IPI-protein kinase binding12874272
GO:0019904IPI-protein domain specific binding11441023
GO:0031625IPI-ubiquitin protein ligase binding17510063
GO:0046332IPI-SMAD binding15107821
GO:0046811ISS-histone deacetylase inhibitor activity-
GO:0070491IPI-repressing transcription factor binding12435627
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter17469184
GO:0000122IMP-negative regulation of transcription from RNA polymerase II promoter12435627
GO:0000122TAS-negative regulation of transcription from RNA polymerase II promoter-
GO:0001843ISS-neural tube closure-
GO:0002089ISS-lens morphogenesis in camera-type eye-
GO:0006351IEA-transcription, DNA-templated-
GO:0007179NAS-transforming growth factor beta receptor signaling pathway14583455
GO:0008283NAS-cell proliferation14583455
GO:0008285IDA-negative regulation of cell proliferation11430826
GO:0009948ISS-anterior/posterior axis specification-
GO:0010626IGI-negative regulation of Schwann cell proliferation15312649
GO:0014902IDA-myotube differentiation19008232
GO:0021772ISS-olfactory bulb development-
GO:0022011ISS-myelination in peripheral nervous system-
GO:0030177NAS-positive regulation of Wnt signaling pathway14583455
GO:0030326ISS-embryonic limb morphogenesis-
GO:0030509TAS-BMP signaling pathway-
GO:0030512IDA-negative regulation of transforming growth factor beta receptor signaling pathway17469184
GO:0030512IGI-negative regulation of transforming growth factor beta receptor signaling pathway15312649
GO:0030512IMP-negative regulation of transforming growth factor beta receptor signaling pathway17054724
GO:0030514IDA-negative regulation of BMP signaling pathway14699069
GO:0030514IMP-negative regulation of BMP signaling pathway17054724
GO:0031064IEA-negative regulation of histone deacetylation-
GO:0032926IDA-negative regulation of activin receptor signaling pathway14699069
GO:0035019ISS-somatic stem cell population maintenance-
GO:0043010ISS-camera-type eye development-
GO:0043388IDA-positive regulation of DNA binding15107821
GO:0043585ISS-nose morphogenesis-
GO:0045668IDA-negative regulation of osteoblast differentiation14699069
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0048147ISS-negative regulation of fibroblast proliferation-
GO:0048593ISS-camera-type eye morphogenesis-
GO:0048666IBA-neuron development-
GO:0048741ISS-skeletal muscle fiber development-
GO:0048870NAS-cell motility14583455
GO:0060021ISS-palate development-
GO:0060041ISS-retina development in camera-type eye-
GO:0060325ISS-face morphogenesis-
GO:0060349ISS-bone morphogenesis-
GO:0060395IDA-SMAD protein signal transduction12874272
GO:0070207IDA-protein homotrimerization8514802
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SKIEYA310844119008232 Affinity Capture-Western
SKIEYA311238819008232 Affinity Capture-Western
SKIGATA110889315542823 Affinity Capture-Western
SKIGATA111238815542823 Affinity Capture-Western
SKIGLI210899812435627 Reconstituted Complex; Two-hybrid
SKIGLI211238812435627 Reconstituted Complex; Two-hybrid
SKIGLI310899912435627 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SKIGLI311238812435627 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SKIJUN10992812034730 Affinity Capture-Western
SKIJUN11238812034730 Affinity Capture-Western
SKISMAD111026112874272 14699069 Affinity Capture-Western; Reconstituted Complex
SKISMAD111238812874272 14699069 Affinity Capture-Western; Reconstituted Complex
SKISMAD211026210485843 10575014 12732634 12874272 14699069 19032343 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SKISMAD211238810485843 10575014 12732634 12874272 14699069 19032343 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SKISMAD311026310575014 11306568 12732634 12857746 12874272 14699069 19032343 Affinity Capture-Western; Reconstituted Complex
SKISMAD311238810575014 11306568 12732634 12857746 12874272 14699069 19032343 Affinity Capture-Western; Reconstituted Complex
SKISMAD411026410531062 12419246 12732634 12857746 12874272 14699069 19032343 Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
SKISMAD411238810531062 12419246 12732634 12857746 12874272 14699069 19032343 Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
SKISMAD511026514699069 Affinity Capture-Western
SKISMAD511238814699069 Affinity Capture-Western
SKIMECP211036811441023 Affinity Capture-Western; Reconstituted Complex
SKIMECP211238811441023 Affinity Capture-Western; Reconstituted Complex
SKIMYB11238814761981 Affinity Capture-Western; Reconstituted Complex
SKIMYB11068714761981 Affinity Capture-Western; Reconstituted Complex
SKINFIX1123889380514 Phenotypic Enhancement; Reconstituted Complex
SKINFIX1108569380514 Phenotypic Enhancement; Reconstituted Complex
SKIPML11138411430826 Affinity Capture-Western; Reconstituted Complex
SKIPML11238811430826 Affinity Capture-Western; Reconstituted Complex
SKIRARA11238816424870 19341714 Affinity Capture-Western; Co-localization
SKIRARA11184916424870 19341714 Affinity Capture-Western; Co-localization
SKIRB11123889988677 Affinity Capture-Western
SKIRB11118609988677 Affinity Capture-Western
SKISIX111238819008232 Affinity Capture-Western
SKISIX111238619008232 Affinity Capture-Western
SNW1SKI1123889569025 11278756 11522815 Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
SNW1SKI1165979569025 11278756 11522815 Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
SKILSKI1123889927733 Affinity Capture-Western; Reconstituted Complex
SKILSKI1123899927733 Affinity Capture-Western; Reconstituted Complex
SKISKI1123889927733 Reconstituted Complex
NCOR1SKI11238811430826 19032343 Affinity Capture-Western; Reconstituted Complex
NCOR1SKI11497311430826 19032343 Affinity Capture-Western; Reconstituted Complex
SIN3ASKI11238811430826 Reconstituted Complex
SIN3ASKI11743911430826 Reconstituted Complex
HIPK2SKI11881512874272 Affinity Capture-Western; Reconstituted Complex
HIPK2SKI11238812874272 Affinity Capture-Western; Reconstituted Complex
TRIM28SKI11545714761981 Reconstituted Complex
TRIM28SKI11238814761981 Reconstituted Complex
UBCSKI11238815806149 Affinity Capture-Western
UBCSKI11316415806149 Affinity Capture-Western
HDAC3SKI11238816987993 17621263 19032343 19341714 Affinity Capture-Western
HDAC3SKI11436816987993 17621263 19032343 19341714 Affinity Capture-Western
SPI1SKI11238817621263 Affinity Capture-Western; Reconstituted Complex
SPI1SKI11256617621263 Affinity Capture-Western; Reconstituted Complex
PRMT5SKI11238819032343 Affinity Capture-Western
PRMT5SKI11568819032343 Affinity Capture-Western
TBL1XR1SKI11238819032343 Affinity Capture-Western
TBL1XR1SKI12283419032343 Affinity Capture-Western
PRDM16SKI11238819049980 Affinity Capture-Western
PRDM16SKI12202319049980 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98310
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990715-10'