Gene Symbol:	SLAMF1 ( CD150,CDw150,SLAM )
Gene Full Name:	signaling lymphocytic activation molecule family member 1
Band:	1q23.3
Quick Links	Entrez ID:6504; OMIM: 603492; Uniprot ID:SLAF1_HUMAN; ENSEMBL ID: ENSG00000117090; HGNC ID: 10903
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0009897	IEA	-	external side of plasma membrane	-
GO:0016021	IEA	-	integral component of membrane	-
GO:0045335	IEA	-	phagocytic vesicle	-
GO:0070062	IDA	-	extracellular exosome	20458337

GO ID	Evidence	Qualifier	GO_term	References
GO:0001618	IEA	-	virus receptor activity	-
GO:0003823	TAS	-	antigen binding	7617038
GO:0004888	TAS	-	transmembrane signaling receptor activity	7617038
GO:0005515	IPI	-	protein binding	9774102
GO:0042802	IEA	-	identical protein binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0001779	IEA	-	natural killer cell differentiation	-
GO:0001787	IEA	-	natural killer cell proliferation	-
GO:0002232	IEA	-	leukocyte chemotaxis involved in inflammatory response	-
GO:0002277	IDA	-	myeloid dendritic cell activation involved in immune response	16317102
GO:0002725	IEA	-	negative regulation of T cell cytokine production	-
GO:0006909	IEA	-	phagocytosis	-
GO:0007155	IEA	-	cell adhesion	-
GO:0007165	IEA	-	signal transduction	-
GO:0008284	TAS	-	positive regulation of cell proliferation	7617038
GO:0010759	IEA	-	positive regulation of macrophage chemotaxis	-
GO:0031338	IEA	-	regulation of vesicle fusion	-
GO:0032695	IDA	-	negative regulation of interleukin-12 production	16317102
GO:0032715	IDA	-	negative regulation of interleukin-6 production	16317102
GO:0032720	IDA	-	negative regulation of tumor necrosis factor production	16317102
GO:0035744	IEA	-	T-helper 1 cell cytokine production	-
GO:0042104	IEA	-	positive regulation of activated T cell proliferation	-
GO:0045087	IEA	-	innate immune response	-
GO:0046330	IDA	-	positive regulation of JNK cascade	20231852
GO:0046718	IEA	-	viral entry into host cell	-
GO:0050790	IEA	-	regulation of catalytic activity	-
GO:0070374	IDA	-	positive regulation of ERK1 and ERK2 cascade	20231852
GO:1902714	IEA	-	negative regulation of interferon-gamma secretion	-
GO:1902715	IEA	-	positive regulation of interferon-gamma secretion	-
GO:2000349	IDA	-	negative regulation of CD40 signaling pathway	16317102
GO:2000510	IEA	-	positive regulation of dendritic cell chemotaxis	-

Gene Symbol	Interactant	Interaction ID	References	Description
SLAMF1	FGR	108559	10229804	Affinity Capture-Western
SLAMF1	FGR	112395	10229804	Affinity Capture-Western
SLAMF1	FYN	108810	12545174	Reconstituted Complex
SLAMF1	FYN	112395	12545174	Reconstituted Complex
SLAMF1	INPP5D	109847	10229804	Affinity Capture-Western
SLAMF1	INPP5D	112395	10229804	Affinity Capture-Western
SLAMF1	SH2D1A	112395	11477068 11806999	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SLAMF1	SH2D1A	110246	11477068 11806999	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SLAMF1	PTPN11	112395	11689425 11806999	Affinity Capture-Western
SLAMF1	PTPN11	111745	11689425 11806999	Affinity Capture-Western
SLAMF1	PTPRC	111752	10229804	Affinity Capture-Western
SLAMF1	PTPRC	112395	10229804	Affinity Capture-Western
SH2D1B	SLAMF1	112395	11689425	Protein-peptide; Two-hybrid
SH2D1B	SLAMF1	125563	11689425	Protein-peptide; Two-hybrid

AutismKB 2.0

Annotation Details for SLAMF1