AutismKB 2.0

Annotation Details for SLC1A2


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Basic Information Top
Gene Symbol:SLC1A2 ( EAAT2,GLT-1 )
Gene Full Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Band: 11p13
Quick LinksEntrez ID:6506; OMIM: 600300; Uniprot ID:EAA2_HUMAN; ENSEMBL ID: ENSG00000110436; HGNC ID: 10940
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0009986IDA-cell surface21399631
GO:0016020TAS-membrane7521911
GO:0016021IEA-integral component of membrane-
GO:0030673IEA-axolemma-
GO ID Evidence Qualifier GO_term References
GO:0005313IDA-L-glutamate transmembrane transporter activity7521911
GO:0005314TAS-high-affinity glutamate transmembrane transporter activity-
GO:0005515IPI-protein binding19527721
GO:0015171TAS-amino acid transmembrane transporter activity-
GO:0015501IEA-glutamate:sodium symporter activity-
GO ID Evidence Qualifier GO_term References
GO:0006811TAS-ion transport-
GO:0007268TAS-chemical synaptic transmission7521911
GO:0007632IEA-visual behavior-
GO:0009611IEA-response to wounding-
GO:0010259IEA-multicellular organism aging-
GO:0014047TAS-glutamate secretion-
GO:0021537IEA-telencephalon development-
GO:0030534IEA-adult behavior-
GO:0031668IEA-cellular response to extracellular stimulus-
GO:0035264IEA-multicellular organism growth-
GO:0042493IEA-response to drug-
GO:0043200IEA-response to amino acid-
GO:0046326IEA-positive regulation of glucose import-
GO:0051938IDA-L-glutamate import7521911
GO:0070779IDA-D-aspartate import7521911
GO:0089711IEA-L-glutamate transmembrane transport-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SLC1A2GRB211239720936779 Two-hybrid
SLC1A2GRB210914220936779 Two-hybrid
JUBSLC1A211239711860269 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
JUBSLC1A212439311860269 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SLC1A2SNP7, rs1042113, rs1570216, rs1885343, rs1923295, rs1923298, rs3838796, rs4534557, rs4755404, rs4756224, rs7110985, rs752949 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:101931
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7779'