AutismKB 2.0

Annotation Details for SLC1A3


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Basic Information Top
Gene Symbol:SLC1A3 ( EA6,EAAT1,FLJ25094,GLAST,GLAST1 )
Gene Full Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Band: 5p13.2
Quick LinksEntrez ID:6507; OMIM: 600111; Uniprot ID:EAA1_HUMAN; ENSEMBL ID: ENSG00000079215; HGNC ID: 10941
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887IMP-integral component of plasma membrane8123008
GO:0009986IEA-cell surface-
GO:0016020TAS-membrane7521911
GO:0043005IEA-neuron projection-
GO:0043025IEA-neuronal cell body-
GO ID Evidence Qualifier GO_term References
GO:0005313IDA-L-glutamate transmembrane transporter activity7521911
GO:0005314IMP-high-affinity glutamate transmembrane transporter activity8123008
GO:0005314TAS-high-affinity glutamate transmembrane transporter activity-
GO:0015171TAS-amino acid transmembrane transporter activity-
GO:0015501IMP-glutamate:sodium symporter activity8123008
GO:0016595IEA-glutamate binding-
GO ID Evidence Qualifier GO_term References
GO:0001504TAS-neurotransmitter uptake8647279
GO:0006537IEA-glutamate biosynthetic process-
GO:0006811TAS-ion transport-
GO:0007268TAS-chemical synaptic transmission7521911
GO:0007605IEA-sensory perception of sound-
GO:0009416IEA-response to light stimulus-
GO:0009449IEA-gamma-aminobutyric acid biosynthetic process-
GO:0009611IEA-response to wounding-
GO:0014047TAS-glutamate secretion-
GO:0021545IEA-cranial nerve development-
GO:0031223IEA-auditory behavior-
GO:0042493IEA-response to drug-
GO:0046677IEA-response to antibiotic-
GO:0048667IEA-cell morphogenesis involved in neuron differentiation-
GO:0050806IEA-positive regulation of synaptic transmission-
GO:0050885IEA-neuromuscular process controlling balance-
GO:0051938IDA-L-glutamate import7521911
GO:0070779IDA-D-aspartate import7521911
GO:0070779IMP-D-aspartate import28032905
GO:0089711IEA-L-glutamate transmembrane transport-
GO:0098712IMP-L-glutamate import across plasma membrane8123008
GO:0140009IMP-L-aspartate import across plasma membrane8123008
GO:0140016IMP-D-aspartate import across plasma membrane8123008
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SLC1A3rs1049524, rs1428973, rs1529461, rs1544795, rs2033267, rs2303716, rs3776585, rs3776586, rs426040, rs4869684, rs962686 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:99917
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2159'