AutismKB 2.0

Annotation Details for RTN4R


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RTN4R ( NGR,NOGOR )
Gene Full Name: reticulon 4 receptor
Band: 22q11.21
Quick LinksEntrez ID:65078; OMIM: 605566; Uniprot ID:RTN4R_HUMAN; ENSEMBL ID: ENSG00000040608; HGNC ID: 18601
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IBA-cytoplasm-
GO:0005783IDA-endoplasmic reticulum-
GO:0005886TAS-plasma membrane-
GO:0005887ISS-integral component of plasma membrane-
GO:0009986IDA-cell surface16712417
GO:0031362IMP-anchored component of external side of plasma membrane16712417
GO:0043005ISS-neuron projection-
GO:0043025ISS-neuronal cell body-
GO:0043198ISS-dendritic shaft-
GO:0043204IEA-perikaryon-
GO:0044295ISS-axonal growth cone-
GO:0045121ISS-membrane raft-
GO:0070062IDA-extracellular exosome23533145
GO ID Evidence Qualifier GO_term References
GO:0004860IBA-protein kinase inhibitor activity-
GO:0004872ISS-receptor activity-
GO:0004872NAS-receptor activity11201742
GO:0005515IPI-protein binding20463223
GO:0008201ISS-heparin binding-
GO:0035374ISS-chondroitin sulfate binding-
GO:0038131ISS-neuregulin receptor activity-
GO:1905573IDA-ganglioside GM1 binding18411262
GO:1905576IDA-ganglioside GT1b binding18411262
GO ID Evidence Qualifier GO_term References
GO:0006469IBA-negative regulation of protein kinase activity-
GO:0007166ISS-cell surface receptor signaling pathway-
GO:0007409IEA-axonogenesis-
GO:0010977ISS-negative regulation of neuron projection development-
GO:0019221IBA-cytokine-mediated signaling pathway-
GO:0022038ISS-corpus callosum development-
GO:0023041ISS-neuronal signal transduction-
GO:0030517ISS-negative regulation of axon extension-
GO:0035025IMP-positive regulation of Rho protein signal transduction16712417
GO:0043547ISS-positive regulation of GTPase activity-
GO:0046426IBA-negative regulation of JAK-STAT cascade-
GO:0048681ISS-negative regulation of axon regeneration-
GO:0050771TAS-negative regulation of axonogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RTN4ROMG11102212068310 Reconstituted Complex
RTN4ROMG12238812068310 Reconstituted Complex
Gene Symbol Interactant Interaction ID References Description
RTN4RTNFRSF1921007715694321 TROY interacts with NgR. This interaction was modelled on a demonstrated interaction between mouse TROY and human NgR.
RTN4RTNFRSF1920941815694322 TROY interacts with NgR.
RTN4RRTN421007815694321 Nogo-66 interacts with NgR.
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
RTN4RRTN4R_V38, rs1567871, rs696880, rs701421, rs701427, rs701428, rs854927, rs854971, rs855051, rs9606296 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:2136886
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040310-1'