AutismKB 2.0

Annotation Details for SLC6A1


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Basic Information Top
Gene Symbol:SLC6A1 ( GABATHG,GABATR,GAT1 )
Gene Full Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Band: 3p25.3
Quick LinksEntrez ID:6529; OMIM: 137165; Uniprot ID:SC6A1_HUMAN; ENSEMBL ID: ENSG00000157103; HGNC ID: 11042
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0009986IEA-cell surface-
GO:0016020TAS-membrane2387399
GO:0016021TAS-integral component of membrane8530094
GO:0030424IEA-axon-
GO:0043005IBA-neuron projection-
GO ID Evidence Qualifier GO_term References
GO:0005328IEA-neurotransmitter:sodium symporter activity-
GO:0005332IBA-gamma-aminobutyric acid:sodium symporter activity-
GO:0005332TAS-gamma-aminobutyric acid:sodium symporter activity-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006810NAS-transport8530094
GO:0006836IEA-neurotransmitter transport-
GO:0007268TAS-chemical synaptic transmission8530094
GO:0007612IEA-learning-
GO:0009636IEA-response to toxic substance-
GO:0009744IEA-response to sucrose-
GO:0010288IEA-response to lead ion-
GO:0014054IEA-positive regulation of gamma-aminobutyric acid secretion-
GO:0014074IEA-response to purine-containing compound-
GO:0015812IBA-gamma-aminobutyric acid transport-
GO:0032229IEA-negative regulation of synaptic transmission, GABAergic-
GO:0032355IEA-response to estradiol-
GO:0042220IEA-response to cocaine-
GO:0051260IEA-protein homooligomerization-
GO:0051592IEA-response to calcium ion-
GO:0051939IEA-gamma-aminobutyric acid import-
GO:0055085IEA-transmembrane transport-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
STX1ASLC6A11126769698305 11017172 11960023 Affinity Capture-Western; Reconstituted Complex
STX1ASLC6A11124209698305 11017172 11960023 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95627
  • Data Attributes: MGI curated and HomoloGene calculated
No data