Gene Symbol:	SLC6A3 ( DAT,DAT1 )
Gene Full Name:	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Band:	5p15.33
Quick Links	Entrez ID:6531; OMIM: 126455; Uniprot ID:SC6A3_HUMAN; ENSEMBL ID: ENSG00000142319; HGNC ID: 11049
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005737	TAS	-	cytoplasm	10823899
GO:0005886	IDA	-	plasma membrane	11343649
GO:0005886	TAS	-	plasma membrane	-
GO:0005887	IBA	-	integral component of plasma membrane	-
GO:0009986	IDA	-	cell surface	21399631
GO:0016021	TAS	-	integral component of membrane	8628395
GO:0016600	IDA	-	flotillin complex	21399631
GO:0030424	IDA	-	axon	12958153
GO:0043005	IDA	-	neuron projection	21957239
GO:0043025	IDA	-	neuronal cell body	12958153
GO:0045121	IDA	-	membrane raft	21957239
GO:0098793	IEA	-	presynapse	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0002020	IEA	-	protease binding	-
GO:0005102	IEA	-	receptor binding	-
GO:0005329	IDA	-	dopamine transmembrane transporter activity	15505207
GO:0005330	IBA	-	dopamine:sodium symporter activity	-
GO:0005515	IPI	-	protein binding	11343649
GO:0008144	IEA	-	drug binding	-
GO:0008504	IDA	-	monoamine transmembrane transporter activity	16024787
GO:0008504	TAS	-	monoamine transmembrane transporter activity	-
GO:0032403	IEA	-	protein complex binding	-
GO:0035240	IEA	-	dopamine binding	-
GO:0046872	IEA	-	metal ion binding	-
GO:0047485	IEA	-	protein N-terminus binding	-
GO:0051721	IEA	-	protein phosphatase 2A binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0007568	IEA	-	aging	-
GO:0007595	IEA	-	lactation	-
GO:0007608	IEA	-	sensory perception of smell	-
GO:0007626	IEA	-	locomotory behavior	-
GO:0010039	IEA	-	response to iron ion	-
GO:0015844	IDA	-	monoamine transport	16024787
GO:0015872	IDA	-	dopamine transport	15505207
GO:0021984	IEA	-	adenohypophysis development	-
GO:0035094	IEA	-	response to nicotine	-
GO:0040018	IEA	-	positive regulation of multicellular organism growth	-
GO:0042053	IEA	-	regulation of dopamine metabolic process	-
GO:0042136	TAS	-	neurotransmitter biosynthetic process	-
GO:0042220	IEA	-	response to cocaine	-
GO:0042416	IEA	-	dopamine biosynthetic process	-
GO:0042420	IEA	-	dopamine catabolic process	-
GO:0042493	IEA	-	response to drug	-
GO:0045471	IEA	-	response to ethanol	-
GO:0051583	IBA	-	dopamine uptake involved in synaptic transmission	-
GO:0051591	IEA	-	response to cAMP	-
GO:0060134	IEA	-	prepulse inhibition	-
GO:0072488	IEA	-	ammonium transmembrane transport	-
GO:0090494	IDA	-	dopamine uptake	21957239

Gene Symbol	Interactant	Interaction ID	References	Description
SLC6A3	EPS15	112422	16885233	Affinity Capture-Western
SLC6A3	EPS15	108374	16885233	Affinity Capture-Western
SLC6A3	NEDD4	112422	16885233	Affinity Capture-Western
SLC6A3	NEDD4	110811	16885233	Affinity Capture-Western
SLC6A3	PARK2	111105	15492001	Affinity Capture-Western
SLC6A3	PARK2	112422	15492001	Affinity Capture-Western
SNCA	SLC6A3	112506	11292651 12672538	Affinity Capture-Western; Two-hybrid
SNCA	SLC6A3	112422	11292651 12672538	Affinity Capture-Western; Two-hybrid
PICK1	SLC6A3	112422	11343649	Affinity Capture-Western; Two-hybrid
PICK1	SLC6A3	114849	11343649	Affinity Capture-Western; Two-hybrid
TGFB1I1	SLC6A3	112422	12177201	Reconstituted Complex; Two-hybrid
TGFB1I1	SLC6A3	112899	12177201	Reconstituted Complex; Two-hybrid
UBC	SLC6A3	113164	15492001 16885233	Affinity Capture-Western
UBC	SLC6A3	112422	15492001 16885233	Affinity Capture-Western
EPN1	SLC6A3	118965	16885233	Affinity Capture-Western
EPN1	SLC6A3	112422	16885233	Affinity Capture-Western

AutismKB 2.0

Annotation Details for SLC6A3