Annotation Details for SLC22A3

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Basic Information Top

Gene Symbol:	SLC22A3 ( EMT,EMTH,OCT3 )
Gene Full Name:	solute carrier family 22 (extraneuronal monoamine transporter), member 3
Band:	6q25.3
Quick Links	Entrez ID:6581; OMIM: 604842; Uniprot ID:S22A3_HUMAN; ENSEMBL ID: ENSG00000146477; HGNC ID: 10967
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:3 results
Molecular Function:8 results
Biological Process:9 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005886	TAS	-	plasma membrane	-
GO:0005887	TAS	-	integral component of plasma membrane	9933568
GO:0016020	TAS	-	membrane	9933568

GO ID	Evidence	Qualifier	GO_term	References
GO:0005329	IBA	-	dopamine transmembrane transporter activity	-
GO:0005515	IPI	-	protein binding	17474147
GO:0008514	IBA	-	organic anion transmembrane transporter activity	-
GO:0015101	EXP	-	organic cation transmembrane transporter activity	19141712
GO:0015101	IDA	-	organic cation transmembrane transporter activity	10966924
GO:0015101	TAS	-	organic cation transmembrane transporter activity	-
GO:0015651	IDA	-	quaternary ammonium group transmembrane transporter activity	10966924
GO:0019534	IEA	-	toxin transporter activity	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0006855	TAS	-	drug transmembrane transport	-
GO:0015695	IDA	-	organic cation transport	10966924
GO:0015697	IDA	-	quaternary ammonium group transport	10966924
GO:0015711	IEA	-	organic anion transport	-
GO:0015872	IBA	-	dopamine transport	-
GO:0032098	IEA	-	regulation of appetite	-
GO:0051615	IEA	-	histamine uptake	-
GO:0072488	IEA	-	ammonium transmembrane transport	-
GO:1901998	IEA	-	toxin transport	-

Protein-Protein Interaction

AlzGene, PDGene and SZGene

Alz Gene:0 results
PD Gene:1 results
SZ Gene:0 results

Gene Symbol	Poly Names	Gene overview in PDGene
SLC22A3	rs2076828, rs2292334	Gene overview in PDGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1333817
Data Attributes: MGI curated and HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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