AutismKB 2.0

Annotation Details for SMARCA2


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Basic Information Top
Gene Symbol:SMARCA2 ( BAF190,BRM,FLJ36757,MGC74511,SNF2,SNF2L2,SNF2LA,SWI2,Sth1p,hBRM,hSNF2a )
Gene Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Band: 9p24.3
Quick LinksEntrez ID:6595; OMIM: 600014; Uniprot ID:SMCA2_HUMAN; ENSEMBL ID: ENSG00000080503; HGNC ID: 11098
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin12065415
GO:0005634IDA-nucleus17984088
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0016514IDA-SWI/SNF complex11078522
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0045111IDA-intermediate filament cytoskeleton-
GO:0071564ISS-npBAF complex-
GO:0071565ISS-nBAF complex-
GO ID Evidence Qualifier GO_term References
GO:0001105IDA-RNA polymerase II transcription coactivator activity17984088
GO:0003682IEA-chromatin binding-
GO:0003713TAS-transcription coactivator activity8223438
GO:0004386IEA-helicase activity-
GO:0005515IPI-protein binding12065415
GO:0005524IEA-ATP binding-
GO:0008094TAS-DNA-dependent ATPase activity17938176
GO:0042393IEA-histone binding-
GO:0044212IDA-transcription regulatory region DNA binding17984088
GO ID Evidence Qualifier GO_term References
GO:0000122TAS-negative regulation of transcription from RNA polymerase II promoter17938176
GO:0006338IMPNOTchromatin remodeling22368283
GO:0006338TAS-chromatin remodeling17938176
GO:0006355TAS-regulation of transcription, DNA-templated8670841
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter8223438
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007286IEA-spermatid development-
GO:0007399IEA-nervous system development-
GO:0008285IDA-negative regulation of cell proliferation14660596
GO:0030308IMP-negative regulation of cell growth12065415
GO:0045892IDA-negative regulation of transcription, DNA-templated12065415
GO:0045893IDA-positive regulation of transcription, DNA-templated17984088
GO:0045893IMP-positive regulation of transcription, DNA-templated8208605
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter15774904
GO:0045944TAS-positive regulation of transcription from RNA polymerase II promoter17938176
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMARCA2ACTL6A1124798895581 11839798 12437990 14559996 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification
SMARCA2ACTL6A1066018895581 11839798 12437990 14559996 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification
SMARCA2ADD111247917074803 Affinity Capture-Western
SMARCA2ADD110663117074803 Affinity Capture-Western
SMARCA2AR11247918487222 19762545 Affinity Capture-Western; Two-hybrid
SMARCA2AR10686218487222 19762545 Affinity Capture-Western; Two-hybrid
SMARCA2BRCA110714015034933 Affinity Capture-Western
SMARCA2BRCA111247915034933 Affinity Capture-Western
SMARCA2CCNE11124799891079 Affinity Capture-Western
SMARCA2CCNE11073389891079 Affinity Capture-Western
SMARCA2CDK81124799710619 Co-fractionation
SMARCA2CDK81074589710619 Co-fractionation
SMARCA2CDX211247919371634 Affinity Capture-Western; Reconstituted Complex
SMARCA2CDX210747519371634 Affinity Capture-Western; Reconstituted Complex
SMARCA2CEBPA11247916452305 Affinity Capture-Western; Reconstituted Complex
SMARCA2CEBPA10747916452305 Affinity Capture-Western; Reconstituted Complex
SMARCA2CEBPB11247910619021 Affinity Capture-Western; Reconstituted Complex
SMARCA2CEBPB10748010619021 Affinity Capture-Western; Reconstituted Complex
SMARCA2CHD310753212453419 Affinity Capture-Western
SMARCA2CHD311247912453419 Affinity Capture-Western
SMARCA2ESR11084039099865 Two-hybrid
SMARCA2ESR11124799099865 Two-hybrid
SMARCA2NR3C111247917043312 Affinity Capture-Western
SMARCA2NR3C110916517043312 Affinity Capture-Western
SMARCA2H2AFX11247916932743 Affinity Capture-Western
SMARCA2H2AFX10926816932743 Affinity Capture-Western
SMARCA2HDAC110931511238380 12453419 Affinity Capture-Western; Co-purification
SMARCA2HDAC111247911238380 12453419 Affinity Capture-Western; Co-purification
SMARCA2HDAC210931611238380 12453419 14559996 Affinity Capture-Western; Co-purification
SMARCA2HDAC211247911238380 12453419 14559996 Affinity Capture-Western; Co-purification
SMARCA2HIF1A10933815347669 Co-localization
SMARCA2HIF1A11247915347669 Co-localization
SMARCA2MECP211247915696166 Affinity Capture-Western; Reconstituted Complex
SMARCA2MECP211036815696166 Affinity Capture-Western; Reconstituted Complex
SMARCA2MYB11247910619021 Reconstituted Complex
SMARCA2MYB11068710619021 Reconstituted Complex
SMARCA2MYC11069414559996 Reconstituted Complex
SMARCA2MYC11247914559996 Reconstituted Complex
SMARCA2NONO11090418042045 Affinity Capture-Western
SMARCA2NONO11247918042045 Affinity Capture-Western
SMARCA2NR4A211098317043312 Affinity Capture-Western; Reconstituted Complex
SMARCA2NR4A211247917043312 Affinity Capture-Western; Reconstituted Complex
SMARCA2PHB11126412065415 15141164 Affinity Capture-Western
SMARCA2PHB11247912065415 15141164 Affinity Capture-Western
SMARCA2PITX111132417043312 Reconstituted Complex
SMARCA2PITX111247917043312 Reconstituted Complex
SMARCA2POLR2A1124798895581 9710619 11238380 16341228 Co-fractionation; Co-localization; Co-purification
SMARCA2POLR2A1114268895581 9710619 11238380 16341228 Co-fractionation; Co-localization; Co-purification
SMARCA2RAN11247912453419 Affinity Capture-Western
SMARCA2RAN11183712453419 Affinity Capture-Western
SMARCA2RBBP411186311238380 12453419 Affinity Capture-Western; Co-purification
SMARCA2RBBP411247911238380 12453419 Affinity Capture-Western; Co-purification
SMARCA2RBBP711247912453419 Affinity Capture-Western
SMARCA2RBBP711186612453419 Affinity Capture-Western
SMARCA2SFPQ11231918042045 Affinity Capture-Western
SMARCA2SFPQ11247918042045 Affinity Capture-Western
SMARCB1SMARCA21124828895581 9744861 11238380 12453419 14559996 18042045 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCB1SMARCA21124798895581 9744861 11238380 12453419 14559996 18042045 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC1SMARCA21124798895581 11238380 12453419 14559996 16230384 16452305 16940996 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC1SMARCA21124838895581 11238380 12453419 14559996 16230384 16452305 16940996 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2SMARCA21124858895581 12453419 14559996 16940996 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2SMARCA21124798895581 12453419 14559996 16940996 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCE1SMARCA21124898895581 14559996 Affinity Capture-MS; Co-purification
SMARCE1SMARCA21124798895581 14559996 Affinity Capture-MS; Co-purification
ARID1ASMARCA21124798895581 14559996 16940996 Affinity Capture-MS; Co-purification
ARID1ASMARCA21138948895581 14559996 16940996 Affinity Capture-MS; Co-purification
SMARCA4SMARCA21124799128241 14559996 18042045 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
SMARCA4SMARCA21124819128241 14559996 18042045 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
SIN3ASMARCA211743911238380 12453419 14559996 15314177 Affinity Capture-Western; Co-purification; Reconstituted Complex
SIN3ASMARCA211247911238380 12453419 14559996 15314177 Affinity Capture-Western; Co-purification; Reconstituted Complex
SSX2SMARCA211247911274403 Affinity Capture-Western
SSX2SMARCA211263511274403 Affinity Capture-Western
SS18SMARCA211247911274403 14603256 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SS18SMARCA211263811274403 14603256 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RUVBL1SMARCA211416611839798 Co-fractionation
RUVBL1SMARCA211247911839798 Co-fractionation
ARID1BSMARCA211247912200431 19279220 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
ARID1BSMARCA212155912200431 19279220 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
ACTL6BSMARCA211952912437990 Affinity Capture-Western
ACTL6BSMARCA211247912437990 Affinity Capture-Western
ALL1SMARCA2114743012453419 Affinity Capture-Western
ALL1SMARCA211247912453419 Affinity Capture-Western
MBD3SMARCA211978812453419 Affinity Capture-Western
MBD3SMARCA211247912453419 Affinity Capture-Western
TAF1SMARCA211273512453419 Affinity Capture-Western
TAF1SMARCA211247912453419 Affinity Capture-Western
TAF6SMARCA211274112453419 Affinity Capture-Western
TAF6SMARCA211247912453419 Affinity Capture-Western
TAF9SMARCA211247912453419 Affinity Capture-Western
TAF9SMARCA211274312453419 Affinity Capture-Western
TBPSMARCA211247912453419 Affinity Capture-Western
TBPSMARCA211277112453419 Affinity Capture-Western
SAP30SMARCA211434612453419 Affinity Capture-Western
SAP30SMARCA211247912453419 Affinity Capture-Western
SMARCD2SMARCA211248714559996 Affinity Capture-MS
SMARCD2SMARCA211247914559996 Affinity Capture-MS
SMARCD1SMARCA211248614559996 18042045 Affinity Capture-MS; Affinity Capture-Western
SMARCD1SMARCA211247914559996 18042045 Affinity Capture-MS; Affinity Capture-Western
PRMT5SMARCA211568814559996 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
PRMT5SMARCA211247914559996 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SIN3BSMARCA211690114559996 Reconstituted Complex
SIN3BSMARCA211247914559996 Reconstituted Complex
NR0B2SMARCA211401215314177 Affinity Capture-Western; Reconstituted Complex
NR0B2SMARCA211247915314177 Affinity Capture-Western; Reconstituted Complex
PRPF6SMARCA211729816341228 Affinity Capture-Western
PRPF6SMARCA211247916341228 Affinity Capture-Western
KHDRBS1SMARCA211247916341228 Affinity Capture-Western; Reconstituted Complex
KHDRBS1SMARCA211590016341228 Affinity Capture-Western; Reconstituted Complex
ZMYND11SMARCA211598916565076 Affinity Capture-Western
ZMYND11SMARCA211247916565076 Affinity Capture-Western
TATSMARCA211276116601680 Affinity Capture-Western; Reconstituted Complex
TATSMARCA211247916601680 Affinity Capture-Western; Reconstituted Complex
BAZ1ASMARCA211634716877760 Affinity Capture-Western
BAZ1ASMARCA211247916877760 Affinity Capture-Western
MCPH1SMARCA212277619525936 Affinity Capture-Western
MCPH1SMARCA211247919525936 Affinity Capture-Western
JOSD2SMARCA212595619615732 Affinity Capture-MS
JOSD2SMARCA211247919615732 Affinity Capture-MS
BANF1SMARCA211247919759913 Affinity Capture-MS
BANF1SMARCA211434219759913 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
SMARCA2PHB5491312065415 Prohibitin interacts with Brm.
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SMARCA2SMARCA2_TNR, rs2296212 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:99603
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5964'