AutismKB 2.0

Annotation Details for HLTF


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Basic Information Top
Gene Symbol:HLTF ( HIP116,HIP116A,HLTF1,RNF80,SMARCA3,SNF2L3,ZBU1 )
Gene Full Name: helicase-like transcription factor
Band: 3q24
Quick LinksEntrez ID:6596; OMIM: 603257; Uniprot ID:HLTF_HUMAN; ENSEMBL ID: ENSG00000071794; HGNC ID: 11099
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005730IEA-nucleolus-
GO:0005737IEA-cytoplasm-
GO:0016020IDA-membrane19946888
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0001077IEA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0003677TAS-DNA binding7876228
GO:0003723IDA-RNA binding22658674
GO:0004386IEA-helicase activity-
GO:0005515IPI-protein binding10391891
GO:0005524IEA-ATP binding-
GO:0008270IEA-zinc ion binding-
GO:0016887IEA-ATPase activity-
GO:0031625IDA-ubiquitin protein ligase binding25023518
GO:0061630EXP-ubiquitin protein ligase activity18316726
GO ID Evidence Qualifier GO_term References
GO:0000209IEA-protein polyubiquitination-
GO:0006301IEA-postreplication repair-
GO:0006355TAS-regulation of transcription, DNA-templated7876228
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0016567TAS-protein ubiquitination-
GO:0016569IEA-covalent chromatin modification-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HLTFEWSR110843120211142 Two-hybrid
HLTFEWSR111248020211142 Two-hybrid
HLTFPCNA11248018316726 Affinity Capture-Western
HLTFPCNA11114218316726 Affinity Capture-Western
WBP4HLTF11636316055720 Affinity Capture-MS
WBP4HLTF11248016055720 Affinity Capture-MS
RPAP1HLTF11248017643375 Affinity Capture-MS
RPAP1HLTF11748717643375 Affinity Capture-MS
RAD18HLTF11248018316726 Affinity Capture-Western; Reconstituted Complex
RAD18HLTF12121218316726 Affinity Capture-Western; Reconstituted Complex
UBE2NHLTF11248018316726 Affinity Capture-Western; Reconstituted Complex
UBE2NHLTF11318218316726 Affinity Capture-Western; Reconstituted Complex
UBE2V2HLTF11248018316726 Affinity Capture-Western; Reconstituted Complex
UBE2V2HLTF11318418316726 Affinity Capture-Western; Reconstituted Complex
USP7HLTF11248019615732 Affinity Capture-MS
USP7HLTF11362219615732 Affinity Capture-MS
UBE2ZHLTF11248019690564 Two-hybrid
UBE2ZHLTF12241919690564 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1196437
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-3306'