AutismKB 2.0

Annotation Details for SMARCB1


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Basic Information Top
Gene Symbol:SMARCB1 ( BAF47,INI1,RDT,RTPS1,SNF5,SNF5L1,Sfh1p,Snr1,hSNFS )
Gene Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Band: 22q11.23
Quick LinksEntrez ID:6598; OMIM: 601607; Uniprot ID:SNF5_HUMAN; ENSEMBL ID: ENSG00000099956; HGNC ID: 11103
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin16217013
GO:0001650IDA-fibrillar center-
GO:0005634IDA-nucleus11430827
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005730IDA-nucleolus22368283
GO:0016514IDA-SWI/SNF complex8804307
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0043234IDA-protein complex16217013
GO:0071564ISS-npBAF complex-
GO:0071565ISS-nBAF complex-
GO ID Evidence Qualifier GO_term References
GO:0000978IDAcontributes_toRNA polymerase II core promoter proximal region sequence-specific DNA binding16217013
GO:0000980IDAcontributes_toRNA polymerase II distal enhancer sequence-specific DNA binding16217013
GO:0001164IMP-RNA polymerase I CORE element sequence-specific DNA binding22368283
GO:0002039IPI-p53 binding11950834
GO:0003677IDA-DNA binding26073604
GO:0003713IMP-transcription coactivator activity16687403
GO:0003713NAS-transcription coactivator activity8804307
GO:0005515IPI-protein binding10078207
GO:0030957IPI-Tat protein binding16687403
GO:0031492IDAcontributes_tonucleosomal DNA binding16217013
GO ID Evidence Qualifier GO_term References
GO:0006281IBA-DNA repair-
GO:0006337IDA-nucleosome disassembly8895581
GO:0006338IDA-chromatin remodeling11726552
GO:0006338IMP-chromatin remodeling22368283
GO:0006351IEA-transcription, DNA-templated-
GO:0006357NAS-regulation of transcription from RNA polymerase II promoter8804307
GO:0007049IEA-cell cycle-
GO:0007399IEA-nervous system development-
GO:0008285IBA-negative regulation of cell proliferation-
GO:0015074TAS-DNA integration7801128
GO:0016569IEA-covalent chromatin modification-
GO:0030154IBA-cell differentiation-
GO:0039692IDA-single stranded viral RNA replication via double stranded DNA intermediate14963118
GO:0043044IDA-ATP-dependent chromatin remodeling16217013
GO:0043923IMP-positive regulation by host of viral transcription16687403
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter11950834
GO:0051091IDA-positive regulation of sequence-specific DNA binding transcription factor activity11950834
GO:0090240IMP-positive regulation of histone H4 acetylation22368283
GO:1900110IMP-negative regulation of histone H3-K9 dimethylation22368283
GO:1900113IMP-negative regulation of histone H3-K9 trimethylation22368283
GO:1901838IGI-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter22368283
GO:1901838IMP-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter22368283
GO:1902661IDA-positive regulation of glucose mediated signaling pathway22368283
GO:2000617IMP-positive regulation of histone H3-K9 acetylation22368283
GO:2000618IMPNOTregulation of histone H4-K16 acetylation22368283
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMARCB1ACTA110657316568092 Affinity Capture-Western
SMARCB1ACTA111248216568092 Affinity Capture-Western
SMARCB1ACTL6A1066018895581 Co-purification
SMARCB1ACTL6A1124828895581 Co-purification
SMARCB1AKT110671016568092 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SMARCB1AKT111248216568092 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SMARCB1ATM11248219805520 Affinity Capture-Western
SMARCB1ATM10696219805520 Affinity Capture-Western
SMARCB1BRCA110714010943845 Co-purification
SMARCB1BRCA111248210943845 Co-purification
SMARCB1CCNE11124829891079 Affinity Capture-Western
SMARCB1CCNE11073389891079 Affinity Capture-Western
SMARCB1CDK81074589710619 Affinity Capture-Western; Co-fractionation
SMARCB1CDK81124829710619 Affinity Capture-Western; Co-fractionation
SMARCB1CDX211248219371634 Reconstituted Complex
SMARCB1CDX210747519371634 Reconstituted Complex
SMARCB1CREBBP1077779584200 9710619 Affinity Capture-Western; Co-fractionation
SMARCB1CREBBP1124829584200 9710619 Affinity Capture-Western; Co-fractionation
SMARCB1EMD10832517620012 Affinity Capture-MS
SMARCB1EMD11248217620012 Affinity Capture-MS
SMARCB1GATA111248211018012 Reconstituted Complex
SMARCB1GATA110889311018012 Reconstituted Complex
SMARCB1HDAC111248211238380 Co-purification
SMARCB1HDAC110931511238380 Co-purification
SMARCB1HDAC211248211238380 Co-purification
SMARCB1HDAC210931611238380 Co-purification
SMARCB1HSF111248211486022 Co-fractionation
SMARCB1HSF110953011486022 Co-fractionation
SMARCB1ING111248211784859 Affinity Capture-MS
SMARCB1ING110983311784859 Affinity Capture-MS
SMARCB1ING211248216387653 Affinity Capture-Western
SMARCB1ING210983416387653 Affinity Capture-Western
SMARCB1MECP211248215696166 Reconstituted Complex
SMARCB1MECP211036815696166 Reconstituted Complex
SMARCB1MLL11248210490642 Affinity Capture-Western
SMARCB1MLL11044310490642 Affinity Capture-Western
SMARCB1MYC11248210319872 14559996 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMARCB1MYC11069410319872 14559996 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMARCB1NONO11248218042045 Reconstituted Complex
SMARCB1NONO11090418042045 Reconstituted Complex
SMARCB1POLR2A1124828895581 9710619 11238380 Co-fractionation; Co-purification
SMARCB1POLR2A1114268895581 9710619 11238380 Co-fractionation; Co-purification
SMARCB1PPP1CA11248212016208 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
SMARCB1PPP1CA11149312016208 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
SMARCB1PPP1CB11248212016208 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
SMARCB1PPP1CB11149412016208 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
SMARCB1PPP1CC11248212016208 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
SMARCB1PPP1CC11149512016208 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex
SMARCB1RAN11248211782423 Reconstituted Complex
SMARCB1RAN11183711782423 Reconstituted Complex
SMARCB1RBBP411248211238380 Co-purification
SMARCB1RBBP411186311238380 Co-purification
SMARCB1RELB11248214743216 Affinity Capture-MS
SMARCB1RELB11190314743216 Affinity Capture-MS
SMARCB1SMARCA21124828895581 9744861 11238380 12453419 14559996 18042045 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCB1SMARCA21124798895581 9744861 11238380 12453419 14559996 18042045 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCB1SMARCA41124828895581 9128241 9584200 9744861 9845365 11238380 11486022 11726552 14559996 15150092 16287714 18042045 18414052 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification
SMARCB1SMARCA41124818895581 9128241 9584200 9744861 9845365 11238380 11486022 11726552 14559996 15150092 16287714 18042045 18414052 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification
SMARCC2SMARCB11124828895581 15150092 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2SMARCB11124858895581 15150092 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification
ARID1ASMARCB11124828895581 11734557 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification
ARID1ASMARCB11138948895581 11734557 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC1SMARCB11124828895581 9584200 9744861 11238380 15150092 16568092 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
SMARCC1SMARCB11124838895581 9584200 9744861 11238380 15150092 16568092 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
SMARCE1SMARCB11124828895581 9845365 16199878 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
SMARCE1SMARCB11124898895581 9845365 16199878 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
KAT2BSMARCB11124829710619 Affinity Capture-Western
KAT2BSMARCB11143759710619 Affinity Capture-Western
MED21SMARCB11148079710619 Affinity Capture-Western
MED21SMARCB11124829710619 Affinity Capture-Western
PPP1R15ASMARCB111717210490642 12016208 Affinity Capture-Western; Reconstituted Complex
PPP1R15ASMARCB111248210490642 12016208 Affinity Capture-Western; Reconstituted Complex
SMARCB1SMARCB111248210943845 Co-purification
NCOR1SMARCB111497311013263 Co-purification
NCOR1SMARCB111248211013263 Co-purification
KLF1SMARCB111590411018012 Reconstituted Complex
KLF1SMARCB111248211018012 Reconstituted Complex
SIN3ASMARCB111743911238380 12453419 14559996 Affinity Capture-Western; Co-purification; Reconstituted Complex
SIN3ASMARCB111248211238380 12453419 14559996 Affinity Capture-Western; Co-purification; Reconstituted Complex
ARID1BSMARCB112155911734557 Affinity Capture-MS
ARID1BSMARCB111248211734557 Affinity Capture-MS
SS18SMARCB111248211734557 Affinity Capture-MS; Affinity Capture-Western
SS18SMARCB111263811734557 Affinity Capture-MS; Affinity Capture-Western
MLLT10SMARCB111248211756182 Affinity Capture-Western
MLLT10SMARCB111372311756182 Affinity Capture-Western
YEATS4SMARCB111248211756182 Affinity Capture-Western; Reconstituted Complex
YEATS4SMARCB111376111756182 Affinity Capture-Western; Reconstituted Complex
XPO1SMARCB111248211782423 Affinity Capture-Western; Reconstituted Complex
XPO1SMARCB111334811782423 Affinity Capture-Western; Reconstituted Complex
TP53SMARCB111248211950834 Affinity Capture-Western; Co-fractionation; Reconstituted Complex
TP53SMARCB111301011950834 Affinity Capture-Western; Co-fractionation; Reconstituted Complex
ALL1SMARCB1114743012453419 Affinity Capture-Western
ALL1SMARCB111248212453419 Affinity Capture-Western
TAF6SMARCB111248212453419 Affinity Capture-Western
TAF6SMARCB111274112453419 Affinity Capture-Western
TACC2SMARCB111583012620397 Affinity Capture-Western
TACC2SMARCB111248212620397 Affinity Capture-Western
BAZ1BSMARCB111449712837248 Affinity Capture-MS; Affinity Capture-Western
BAZ1BSMARCB111248212837248 Affinity Capture-MS; Affinity Capture-Western
PRMT5SMARCB111568814559996 Reconstituted Complex
PRMT5SMARCB111248214559996 Reconstituted Complex
SIN3BSMARCB111690114559996 Reconstituted Complex
SIN3BSMARCB111248214559996 Reconstituted Complex
CARM1SMARCB111576014729568 Co-purification
CARM1SMARCB111248214729568 Co-purification
BCL2L11SMARCB111533515096481 Reconstituted Complex
BCL2L11SMARCB111248215096481 Reconstituted Complex
NR0B2SMARCB111401215314177 Reconstituted Complex
NR0B2SMARCB111248215314177 Reconstituted Complex
UBQLN4SMARCB112122316169070 Two-hybrid
UBQLN4SMARCB111248216169070 Two-hybrid
TATSMARCB111248216601680 Affinity Capture-Western; Reconstituted Complex
TATSMARCB111276116601680 Affinity Capture-Western; Reconstituted Complex
SMARCD1SMARCB111248218042045 Affinity Capture-Western
SMARCD1SMARCB111248618042045 Affinity Capture-Western
BCL7CSMARCB111469118809673 Affinity Capture-MS
BCL7CSMARCB111248218809673 Affinity Capture-MS
CDYLSMARCB111481819061646 Affinity Capture-MS
CDYLSMARCB111248219061646 Affinity Capture-MS
MLL4SMARCB111510419221051 Reconstituted Complex
MLL4SMARCB111248219221051 Reconstituted Complex
MLL3SMARCB112183519221051 Reconstituted Complex; Two-hybrid
MLL3SMARCB111248219221051 Reconstituted Complex; Two-hybrid
MCPH1SMARCB112277619525936 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
MCPH1SMARCB111248219525936 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
XPCSMARCB111248219805520 Affinity Capture-Western; Co-localization
XPCSMARCB111334519805520 Affinity Capture-Western; Co-localization
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1328366
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041114-5'