AutismKB 2.0

Annotation Details for SMARCC1


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Basic Information Top
Gene Symbol:SMARCC1 ( BAF155,CRACC1,Rsc8,SRG3,SWI3 )
Gene Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Band: 3p21.31
Quick LinksEntrez ID:6599; OMIM: 601732; Uniprot ID:SMRC1_HUMAN; ENSEMBL ID: ENSG00000173473; HGNC ID: 11104
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin16217013
GO:0001741IEA-XY body-
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0016514IDA-SWI/SNF complex8804307
GO:0043234IDA-protein complex16217013
GO:0071564ISS-npBAF complex-
GO:0071565ISS-nBAF complex-
GO ID Evidence Qualifier GO_term References
GO:0000978IDAcontributes_toRNA polymerase II core promoter proximal region sequence-specific DNA binding16217013
GO:0000980IDAcontributes_toRNA polymerase II distal enhancer sequence-specific DNA binding16217013
GO:0003713NAS-transcription coactivator activity8804307
GO:0005515IPI-protein binding9891079
GO:0031492IDAcontributes_tonucleosomal DNA binding16217013
GO:0047485IPI-protein N-terminus binding12917342
GO ID Evidence Qualifier GO_term References
GO:0006337IDA-nucleosome disassembly8895581
GO:0006338IDA-chromatin remodeling10078207
GO:0006351IEA-transcription, DNA-templated-
GO:0006357NAS-regulation of transcription from RNA polymerase II promoter8804307
GO:0007399IEA-nervous system development-
GO:0008286IEA-insulin receptor signaling pathway-
GO:0009887IEA-animal organ morphogenesis-
GO:0016569IEA-covalent chromatin modification-
GO:0030850IEA-prostate gland development-
GO:0032435IEA-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-
GO:0043044IDA-ATP-dependent chromatin remodeling16217013
GO:0045893IDA-positive regulation of transcription, DNA-templated11018012
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMARCC1ADD110663117074803 Affinity Capture-Western; Reconstituted Complex
SMARCC1ADD111248317074803 Affinity Capture-Western; Reconstituted Complex
SMARCC1AKT110671016568092 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SMARCC1AKT111248316568092 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SMARCC1AR10686214966121 Affinity Capture-Western
SMARCC1AR11248314966121 Affinity Capture-Western
SMARCC1BRCA110714010943845 Co-purification
SMARCC1BRCA111248310943845 Co-purification
SMARCC1CCNE11073389891079 Affinity Capture-Western
SMARCC1CCNE11124839891079 Affinity Capture-Western
SMARCC1CDK81074589710619 Co-fractionation
SMARCC1CDK81124839710619 Co-fractionation
SMARCC1CEBPB10748010619021 Affinity Capture-Western
SMARCC1CEBPB11248310619021 Affinity Capture-Western
SMARCC1CHD410753311003653 16217013 Affinity Capture-Western
SMARCC1CHD411248311003653 16217013 Affinity Capture-Western
SMARCC1CREBBP1077779584200 Affinity Capture-Western
SMARCC1CREBBP1124839584200 Affinity Capture-Western
SMARCC1EMD10832517620012 Affinity Capture-MS
SMARCC1EMD11248317620012 Affinity Capture-MS
SMARCC1GATA110889311018012 Reconstituted Complex
SMARCC1GATA111248311018012 Reconstituted Complex
SMARCC1NR3C111248312917342 Affinity Capture-Western
SMARCC1NR3C110916512917342 Affinity Capture-Western
SMARCC1NR4A110940719321449 Affinity Capture-MS
SMARCC1NR4A111248319321449 Affinity Capture-MS
SMARCC1HNRNPC11248316217013 Affinity Capture-Western
SMARCC1HNRNPC10942416217013 Affinity Capture-Western
SMARCC1ING110983311784859 Affinity Capture-MS; Affinity Capture-Western
SMARCC1ING111248311784859 Affinity Capture-MS; Affinity Capture-Western
SMARCC1ING210983416387653 Affinity Capture-Western
SMARCC1ING211248316387653 Affinity Capture-Western
SMARCC1SMAD211026218003620 Affinity Capture-MS
SMARCC1SMAD211248318003620 Affinity Capture-MS
SMARCC1SMAD311026318003620 Affinity Capture-MS
SMARCC1SMAD311248318003620 Affinity Capture-MS
SMARCC1MYC11069414559996 Reconstituted Complex
SMARCC1MYC11248314559996 Reconstituted Complex
SMARCC1NEDD411081116055720 Affinity Capture-MS
SMARCC1NEDD411248316055720 Affinity Capture-MS
SMARCC1NONO11090418042045 Reconstituted Complex
SMARCC1NONO11248318042045 Reconstituted Complex
SMARCC1RELB11190314743216 Affinity Capture-MS
SMARCC1RELB11248314743216 Affinity Capture-MS
SMARCC1SMARCA21124798895581 11238380 12453419 14559996 16230384 16452305 16940996 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC1SMARCA21124838895581 11238380 12453419 14559996 16230384 16452305 16940996 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC1SMARCA41124838895581 9584200 9845365 11238380 11726552 14559996 16217013 16230384 16287714 16452305 18086889 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC1SMARCA41124818895581 9584200 9845365 11238380 11726552 14559996 16217013 16230384 16287714 16452305 18086889 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC1SMARCB11124828895581 9584200 9744861 11238380 15150092 16568092 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
SMARCC1SMARCB11124838895581 9584200 9744861 11238380 15150092 16568092 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
SMARCE1SMARCC11124899845365 16199878 16940996 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMARCE1SMARCC11124839845365 16199878 16940996 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
NCOR1SMARCC111248311013263 Co-purification
NCOR1SMARCC111497311013263 Co-purification
KLF1SMARCC111248311018012 Reconstituted Complex
KLF1SMARCC111590411018012 Reconstituted Complex
SP1SMARCC111255011018012 Reconstituted Complex
SP1SMARCC111248311018012 Reconstituted Complex
SIN3ASMARCC111248311238380 11784859 12453419 Affinity Capture-Western; Reconstituted Complex
SIN3ASMARCC111743911238380 11784859 12453419 Affinity Capture-Western; Reconstituted Complex
HSP90B1SMARCC111303611726552 Affinity Capture-Western
HSP90B1SMARCC111248311726552 Affinity Capture-Western
TP53SMARCC111248311950834 Co-fractionation
TP53SMARCC111301011950834 Co-fractionation
STAT2SMARCC111265012244326 Affinity Capture-Western
STAT2SMARCC111248312244326 Affinity Capture-Western
ALL1SMARCC1114743012453419 Affinity Capture-Western
ALL1SMARCC111248312453419 Affinity Capture-Western
TAF6SMARCC111274112453419 Affinity Capture-Western
TAF6SMARCC111248312453419 Affinity Capture-Western
BAZ1BSMARCC111449712837248 Affinity Capture-MS; Affinity Capture-Western
BAZ1BSMARCC111248312837248 Affinity Capture-MS; Affinity Capture-Western
SMARCD1SMARCC111248612917342 Affinity Capture-Western
SMARCD1SMARCC111248312917342 Affinity Capture-Western
PRMT5SMARCC111568814559996 Reconstituted Complex
PRMT5SMARCC111248314559996 Reconstituted Complex
CARM1SMARCC111576014729568 Affinity Capture-Western; Co-purification
CARM1SMARCC111248314729568 Affinity Capture-Western; Co-purification
ARID1BSMARCC111248315170388 16230384 20086098 Affinity Capture-MS; Affinity Capture-Western
ARID1BSMARCC112155915170388 16230384 20086098 Affinity Capture-MS; Affinity Capture-Western
ARID1ASMARCC111248315170388 16230384 19650111 Affinity Capture-Western
ARID1ASMARCC111389415170388 16230384 19650111 Affinity Capture-Western
NR0B2SMARCC111401215314177 Affinity Capture-Western
NR0B2SMARCC111248315314177 Affinity Capture-Western
SRCSMARCC111259215923603 Far Western; Reconstituted Complex
SRCSMARCC111248315923603 Far Western; Reconstituted Complex
WWOXSMARCC111248316055720 Affinity Capture-MS
WWOXSMARCC111970716055720 Affinity Capture-MS
ITCHSMARCC112374716055720 Affinity Capture-MS
ITCHSMARCC111248316055720 Affinity Capture-MS
SRRM2SMARCC111707116159877 Affinity Capture-MS
SRRM2SMARCC111248316159877 Affinity Capture-MS
SMARCC2SMARCC111248516230384 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western
SMARCC2SMARCC111248316230384 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western
SMARCC1SMARCC111248316230384 Affinity Capture-Western
TATSMARCC111276116601680 Reconstituted Complex
TATSMARCC111248316601680 Reconstituted Complex
TAF10SMARCC111274417643375 Affinity Capture-MS
TAF10SMARCC111248317643375 Affinity Capture-MS
BCL7CSMARCC111469118809673 Affinity Capture-MS
BCL7CSMARCC111248318809673 Affinity Capture-MS
BRD7SMARCC111888318809673 Affinity Capture-Western
BRD7SMARCC111248318809673 Affinity Capture-Western
MCPH1SMARCC112277619525936 Affinity Capture-MS; Affinity Capture-Western
MCPH1SMARCC111248319525936 Affinity Capture-MS; Affinity Capture-Western
PBRM1SMARCC111248319650111 Affinity Capture-Western
PBRM1SMARCC112049019650111 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SMARCC1rs4274776 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1203524
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060503-273'