AutismKB 2.0

Annotation Details for DDRGK1


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Basic Information Top
Gene Symbol:DDRGK1 ( C20orf116,MGC2592,dJ1187M17.3 )
Gene Full Name: DDRGK domain containing 1
Band: 20p13
Quick LinksEntrez ID:65992; OMIM: NA; Uniprot ID:DDRGK_HUMAN; ENSEMBL ID: ENSG00000198171; HGNC ID: 16110
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005730IDA-nucleolus-
GO:0005737TAS-cytoplasm23675531
GO:0005783IDA-endoplasmic reticulum20018847
GO:0005789IDA-endoplasmic reticulum membrane20228063
GO ID Evidence Qualifier GO_term References
GO:0001103IDA-RNA polymerase II repressing transcription factor binding23675531
GO:0005515IPI-protein binding20018847
GO:0044389IPI-ubiquitin-like protein ligase binding25219498
GO ID Evidence Qualifier GO_term References
GO:0008284IMP-positive regulation of cell proliferation23675531
GO:0010628IMP-positive regulation of gene expression23675531
GO:0010629IMP-negative regulation of gene expression23675531
GO:0030335IMP-positive regulation of cell migration23675531
GO:0032436IMP-positive regulation of proteasomal ubiquitin-dependent protein catabolic process23675531
GO:0033146IDA-regulation of intracellular estrogen receptor signaling pathway25219498
GO:0034976ISS-response to endoplasmic reticulum stress-
GO:0043066ISS-negative regulation of apoptotic process-
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter23675531
GO:0051092IMP-positive regulation of NF-kappaB transcription factor activity23675531
GO:1901800IMP-positive regulation of proteasomal protein catabolic process23675531
GO:1902808IC-positive regulation of cell cycle G1/S phase transition23675531
GO:1903721IMP-positive regulation of I-kappaB phosphorylation23675531
GO:1905050IMP-positive regulation of metallopeptidase activity23675531
GO:1905552ISS-positive regulation of protein localization to endoplasmic reticulum-
GO:1905636IMP-positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding23675531
GO:1990592IDA-protein K69-linked ufmylation25219498
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CDK5RAP3DDRGK112244117353931 Affinity Capture-MS
CDK5RAP3DDRGK112321317353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1924256
  • Data Attributes: HomoloGene calculated
No data