AutismKB 2.0

Annotation Details for TMEM108


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Basic Information Top
Gene Symbol:TMEM108 ( CT124,MGC3040 )
Gene Full Name: transmembrane protein 108
Band: 3q22.1
Quick LinksEntrez ID:66000; OMIM: NA; Uniprot ID:TM108_HUMAN; ENSEMBL ID: ENSG00000144868; HGNC ID: 28451
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005575ND-cellular_component-
GO:0005769ISS-early endosome-
GO:0010008ISS-endosome membrane-
GO:0014069ISS-postsynaptic density-
GO:0016021IEA-integral component of membrane-
GO:0030054IEA-cell junction-
GO:0030424ISS-axon-
GO:0030425IEA-dendrite-
GO:0036477ISS-somatodendritic compartment-
GO:0045211IEA-postsynaptic membrane-
GO:1904115IEA-axon cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0003674ND-molecular_function-
GO ID Evidence Qualifier GO_term References
GO:0006898ISS-receptor-mediated endocytosis-
GO:0008090ISS-retrograde axonal transport-
GO:0008150ND-biological_process-
GO:0021542ISS-dentate gyrus development-
GO:0031175ISS-neuron projection development-
GO:0051388ISS-positive regulation of neurotrophin TRK receptor signaling pathway-
GO:0097106ISS-postsynaptic density organization-
GO:0097484ISS-dendrite extension-
GO:0098815ISS-modulation of excitatory postsynaptic potential-
GO:1990416ISS-cellular response to brain-derived neurotrophic factor stimulus-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
TMEM108rs7624858 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1932411
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018