AutismKB 2.0

Annotation Details for SMARCC2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SMARCC2 ( BAF170,CRACC2,DKFZp313D0632,Rsc8 )
Gene Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Band: 12q13.2
Quick LinksEntrez ID:6601; OMIM: 601734; Uniprot ID:SMRC2_HUMAN; ENSEMBL ID: ENSG00000139613; HGNC ID: 11105
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin16217013
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0016514IDA-SWI/SNF complex8804307
GO:0017053IPIcolocalizes_withtranscriptional repressor complex12192000
GO:0043234IDA-protein complex16217013
GO:0071564ISS-npBAF complex-
GO:0071565ISS-nBAF complex-
GO ID Evidence Qualifier GO_term References
GO:0000978IDAcontributes_toRNA polymerase II core promoter proximal region sequence-specific DNA binding16217013
GO:0000980IDAcontributes_toRNA polymerase II distal enhancer sequence-specific DNA binding16217013
GO:0003713NAS-transcription coactivator activity8804307
GO:0005515IPI-protein binding12192000
GO:0031492IDAcontributes_tonucleosomal DNA binding16217013
GO ID Evidence Qualifier GO_term References
GO:0006337IDA-nucleosome disassembly8895581
GO:0006338IDA-chromatin remodeling10078207
GO:0006351IEA-transcription, DNA-templated-
GO:0006357NAS-regulation of transcription from RNA polymerase II promoter8804307
GO:0007399IEA-nervous system development-
GO:0016569IEA-covalent chromatin modification-
GO:0043044IDA-ATP-dependent chromatin remodeling16217013
GO:0045892IDA-negative regulation of transcription, DNA-templated12192000
GO:0045893IDA-positive regulation of transcription, DNA-templated11018012
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMARCC2ACTB1065759845365 Affinity Capture-Western
SMARCC2ACTB1124859845365 Affinity Capture-Western
SMARCC2AKT111248516568092 Affinity Capture-Western
SMARCC2AKT110671016568092 Affinity Capture-Western
SMARCC2ARRB210690216169070 Two-hybrid
SMARCC2ARRB211248516169070 Two-hybrid
SMARCC2BRCA110714010943845 Co-purification
SMARCC2BRCA111248510943845 Co-purification
SMARCC2CDK81124859710619 Co-fractionation
SMARCC2CDK81074589710619 Co-fractionation
SMARCC2CREBBP1124859584200 Affinity Capture-Western
SMARCC2CREBBP1077779584200 Affinity Capture-Western
SMARCC2EMD11248517620012 Affinity Capture-MS
SMARCC2EMD10832517620012 Affinity Capture-MS
SMARCC2GATA110889311018012 Reconstituted Complex
SMARCC2GATA111248511018012 Reconstituted Complex
SMARCC2HDAC110931512192000 Affinity Capture-Western
SMARCC2HDAC111248512192000 Affinity Capture-Western
SMARCC2HDAC210931612192000 Affinity Capture-Western
SMARCC2HDAC211248512192000 Affinity Capture-Western
SMARCC2ING110983311784859 Affinity Capture-MS
SMARCC2ING111248511784859 Affinity Capture-MS
SMARCC2ING210983416387653 Affinity Capture-Western
SMARCC2ING211248516387653 Affinity Capture-Western
SMARCC2SMAD211248518003620 Affinity Capture-MS
SMARCC2SMAD211026218003620 Affinity Capture-MS
SMARCC2SMAD311026318003620 Affinity Capture-MS; Affinity Capture-Western
SMARCC2SMAD311248518003620 Affinity Capture-MS; Affinity Capture-Western
SMARCC2PEX1411248516169070 Two-hybrid
SMARCC2PEX1411121816169070 Two-hybrid
SMARCC2POLR2C11248516169070 Two-hybrid
SMARCC2POLR2C11142816169070 Two-hybrid
SMARCC2RELB11248514743216 Affinity Capture-MS
SMARCC2RELB11190314743216 Affinity Capture-MS
SMARCC2REST11191012192000 Affinity Capture-Western
SMARCC2REST11248512192000 Affinity Capture-Western
SMARCC2ITSN111248516169070 Two-hybrid
SMARCC2ITSN111235116169070 Two-hybrid
SMARCC2SMARCA21124858895581 12453419 14559996 16940996 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2SMARCA21124798895581 12453419 14559996 16940996 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2SMARCA41124858895581 9845365 11726552 14559996 18086889 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2SMARCA41124818895581 9845365 11726552 14559996 18086889 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2SMARCB11124828895581 15150092 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2SMARCB11124858895581 15150092 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2SMARCC111248516230384 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western
SMARCC2SMARCC111248316230384 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western
SMARCE1SMARCC21124899845365 16199878 16940996 18809673 19164553 19650111 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMARCE1SMARCC21124859845365 16199878 16940996 18809673 19164553 19650111 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
NCOR1SMARCC211248511013263 Co-purification
NCOR1SMARCC211497311013263 Co-purification
KLF1SMARCC211590411018012 Reconstituted Complex
KLF1SMARCC211248511018012 Reconstituted Complex
SP1SMARCC211248511018012 Reconstituted Complex
SP1SMARCC211255011018012 Reconstituted Complex
HSP90B1SMARCC211303611726552 Affinity Capture-Western
HSP90B1SMARCC211248511726552 Affinity Capture-Western
RCOR1SMARCC211679612192000 Affinity Capture-Western
RCOR1SMARCC211248512192000 Affinity Capture-Western
STAT2SMARCC211265012244326 Affinity Capture-Western
STAT2SMARCC211248512244326 Affinity Capture-Western
ALL1SMARCC2114743012453419 Affinity Capture-Western
ALL1SMARCC211248512453419 Affinity Capture-Western
SIN3ASMARCC211743912453419 Affinity Capture-Western
SIN3ASMARCC211248512453419 Affinity Capture-Western
TAF6SMARCC211274112453419 Affinity Capture-Western
TAF6SMARCC211248512453419 Affinity Capture-Western
BAZ1BSMARCC211449712837248 Affinity Capture-MS; Affinity Capture-Western
BAZ1BSMARCC211248512837248 Affinity Capture-MS; Affinity Capture-Western
SMARCD1SMARCC211248612917342 Affinity Capture-Western
SMARCD1SMARCC211248512917342 Affinity Capture-Western
CARM1SMARCC211576014729568 Affinity Capture-Western; Co-purification
CARM1SMARCC211248514729568 Affinity Capture-Western; Co-purification
ITCHSMARCC212374716055720 Affinity Capture-MS
ITCHSMARCC211248516055720 Affinity Capture-MS
SRRM1SMARCC211554416159877 Affinity Capture-MS
SRRM1SMARCC211248516159877 Affinity Capture-MS
PHYHIPSMARCC211513916169070 Two-hybrid
PHYHIPSMARCC211248516169070 Two-hybrid
TATSMARCC211276116601680 Reconstituted Complex
TATSMARCC211248516601680 Reconstituted Complex
TAF13SMARCC211248517643375 Affinity Capture-MS
TAF13SMARCC211274717643375 Affinity Capture-MS
TOPORSSMARCC211550517803295 Affinity Capture-MS
TOPORSSMARCC211248517803295 Affinity Capture-MS
ADNPSMARCC211696717878164 Affinity Capture-MS
ADNPSMARCC211248517878164 Affinity Capture-MS
KDM5BSMARCC211598419336002 Affinity Capture-MS
KDM5BSMARCC211248519336002 Affinity Capture-MS
MCPH1SMARCC212277619525936 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
MCPH1SMARCC211248519525936 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
PBRM1SMARCC211248519650111 Affinity Capture-Western
PBRM1SMARCC212049019650111 Affinity Capture-Western
ARID1ASMARCC211248519650111 Affinity Capture-Western
ARID1ASMARCC211389419650111 Affinity Capture-Western
BANF1SMARCC211248519759913 Affinity Capture-MS
BANF1SMARCC211434219759913 Affinity Capture-MS
ARID1BSMARCC211248520086098 Affinity Capture-MS; Affinity Capture-Western
ARID1BSMARCC212155920086098 Affinity Capture-MS; Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1915344
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-100728-1'