Gene Symbol:	SMARCC2 ( BAF170,CRACC2,DKFZp313D0632,Rsc8 )
Gene Full Name:	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Band:	12q13.2
Quick Links	Entrez ID:6601; OMIM: 601734; Uniprot ID:SMRC2_HUMAN; ENSEMBL ID: ENSG00000139613; HGNC ID: 11105
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0000790	IDA	-	nuclear chromatin	16217013
GO:0005654	IDA	-	nucleoplasm	-
GO:0005654	TAS	-	nucleoplasm	-
GO:0016514	IDA	-	SWI/SNF complex	8804307
GO:0017053	IPI	colocalizes_with	transcriptional repressor complex	12192000
GO:0043234	IDA	-	protein complex	16217013
GO:0071564	ISS	-	npBAF complex	-
GO:0071565	ISS	-	nBAF complex	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000978	IDA	contributes_to	RNA polymerase II core promoter proximal region sequence-specific DNA binding	16217013
GO:0000980	IDA	contributes_to	RNA polymerase II distal enhancer sequence-specific DNA binding	16217013
GO:0003713	NAS	-	transcription coactivator activity	8804307
GO:0005515	IPI	-	protein binding	12192000
GO:0031492	IDA	contributes_to	nucleosomal DNA binding	16217013

GO ID	Evidence	Qualifier	GO_term	References
GO:0006337	IDA	-	nucleosome disassembly	8895581
GO:0006338	IDA	-	chromatin remodeling	10078207
GO:0006351	IEA	-	transcription, DNA-templated	-
GO:0006357	NAS	-	regulation of transcription from RNA polymerase II promoter	8804307
GO:0007399	IEA	-	nervous system development	-
GO:0016569	IEA	-	covalent chromatin modification	-
GO:0043044	IDA	-	ATP-dependent chromatin remodeling	16217013
GO:0045892	IDA	-	negative regulation of transcription, DNA-templated	12192000
GO:0045893	IDA	-	positive regulation of transcription, DNA-templated	11018012

Gene Symbol	Interactant	Interaction ID	References	Description
SMARCC2	ACTB	106575	9845365	Affinity Capture-Western
SMARCC2	ACTB	112485	9845365	Affinity Capture-Western
SMARCC2	AKT1	112485	16568092	Affinity Capture-Western
SMARCC2	AKT1	106710	16568092	Affinity Capture-Western
SMARCC2	ARRB2	106902	16169070	Two-hybrid
SMARCC2	ARRB2	112485	16169070	Two-hybrid
SMARCC2	BRCA1	107140	10943845	Co-purification
SMARCC2	BRCA1	112485	10943845	Co-purification
SMARCC2	CDK8	112485	9710619	Co-fractionation
SMARCC2	CDK8	107458	9710619	Co-fractionation
SMARCC2	CREBBP	112485	9584200	Affinity Capture-Western
SMARCC2	CREBBP	107777	9584200	Affinity Capture-Western
SMARCC2	EMD	112485	17620012	Affinity Capture-MS
SMARCC2	EMD	108325	17620012	Affinity Capture-MS
SMARCC2	GATA1	108893	11018012	Reconstituted Complex
SMARCC2	GATA1	112485	11018012	Reconstituted Complex
SMARCC2	HDAC1	109315	12192000	Affinity Capture-Western
SMARCC2	HDAC1	112485	12192000	Affinity Capture-Western
SMARCC2	HDAC2	109316	12192000	Affinity Capture-Western
SMARCC2	HDAC2	112485	12192000	Affinity Capture-Western
SMARCC2	ING1	109833	11784859	Affinity Capture-MS
SMARCC2	ING1	112485	11784859	Affinity Capture-MS
SMARCC2	ING2	109834	16387653	Affinity Capture-Western
SMARCC2	ING2	112485	16387653	Affinity Capture-Western
SMARCC2	SMAD2	112485	18003620	Affinity Capture-MS
SMARCC2	SMAD2	110262	18003620	Affinity Capture-MS
SMARCC2	SMAD3	110263	18003620	Affinity Capture-MS; Affinity Capture-Western
SMARCC2	SMAD3	112485	18003620	Affinity Capture-MS; Affinity Capture-Western
SMARCC2	PEX14	112485	16169070	Two-hybrid
SMARCC2	PEX14	111218	16169070	Two-hybrid
SMARCC2	POLR2C	112485	16169070	Two-hybrid
SMARCC2	POLR2C	111428	16169070	Two-hybrid
SMARCC2	RELB	112485	14743216	Affinity Capture-MS
SMARCC2	RELB	111903	14743216	Affinity Capture-MS
SMARCC2	REST	111910	12192000	Affinity Capture-Western
SMARCC2	REST	112485	12192000	Affinity Capture-Western
SMARCC2	ITSN1	112485	16169070	Two-hybrid
SMARCC2	ITSN1	112351	16169070	Two-hybrid
SMARCC2	SMARCA2	112485	8895581 12453419 14559996 16940996	Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2	SMARCA2	112479	8895581 12453419 14559996 16940996	Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2	SMARCA4	112485	8895581 9845365 11726552 14559996 18086889 18809673	Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2	SMARCA4	112481	8895581 9845365 11726552 14559996 18086889 18809673	Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2	SMARCB1	112482	8895581 15150092 18809673 19650111	Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2	SMARCB1	112485	8895581 15150092 18809673 19650111	Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCC2	SMARCC1	112485	16230384 18809673 19650111	Affinity Capture-MS; Affinity Capture-Western
SMARCC2	SMARCC1	112483	16230384 18809673 19650111	Affinity Capture-MS; Affinity Capture-Western
SMARCE1	SMARCC2	112489	9845365 16199878 16940996 18809673 19164553 19650111	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMARCE1	SMARCC2	112485	9845365 16199878 16940996 18809673 19164553 19650111	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
NCOR1	SMARCC2	112485	11013263	Co-purification
NCOR1	SMARCC2	114973	11013263	Co-purification
KLF1	SMARCC2	115904	11018012	Reconstituted Complex
KLF1	SMARCC2	112485	11018012	Reconstituted Complex
SP1	SMARCC2	112485	11018012	Reconstituted Complex
SP1	SMARCC2	112550	11018012	Reconstituted Complex
HSP90B1	SMARCC2	113036	11726552	Affinity Capture-Western
HSP90B1	SMARCC2	112485	11726552	Affinity Capture-Western
RCOR1	SMARCC2	116796	12192000	Affinity Capture-Western
RCOR1	SMARCC2	112485	12192000	Affinity Capture-Western
STAT2	SMARCC2	112650	12244326	Affinity Capture-Western
STAT2	SMARCC2	112485	12244326	Affinity Capture-Western
ALL1	SMARCC2	1147430	12453419	Affinity Capture-Western
ALL1	SMARCC2	112485	12453419	Affinity Capture-Western
SIN3A	SMARCC2	117439	12453419	Affinity Capture-Western
SIN3A	SMARCC2	112485	12453419	Affinity Capture-Western
TAF6	SMARCC2	112741	12453419	Affinity Capture-Western
TAF6	SMARCC2	112485	12453419	Affinity Capture-Western
BAZ1B	SMARCC2	114497	12837248	Affinity Capture-MS; Affinity Capture-Western
BAZ1B	SMARCC2	112485	12837248	Affinity Capture-MS; Affinity Capture-Western
SMARCD1	SMARCC2	112486	12917342	Affinity Capture-Western
SMARCD1	SMARCC2	112485	12917342	Affinity Capture-Western
CARM1	SMARCC2	115760	14729568	Affinity Capture-Western; Co-purification
CARM1	SMARCC2	112485	14729568	Affinity Capture-Western; Co-purification
ITCH	SMARCC2	123747	16055720	Affinity Capture-MS
ITCH	SMARCC2	112485	16055720	Affinity Capture-MS
SRRM1	SMARCC2	115544	16159877	Affinity Capture-MS
SRRM1	SMARCC2	112485	16159877	Affinity Capture-MS
PHYHIP	SMARCC2	115139	16169070	Two-hybrid
PHYHIP	SMARCC2	112485	16169070	Two-hybrid
TAT	SMARCC2	112761	16601680	Reconstituted Complex
TAT	SMARCC2	112485	16601680	Reconstituted Complex
TAF13	SMARCC2	112485	17643375	Affinity Capture-MS
TAF13	SMARCC2	112747	17643375	Affinity Capture-MS
TOPORS	SMARCC2	115505	17803295	Affinity Capture-MS
TOPORS	SMARCC2	112485	17803295	Affinity Capture-MS
ADNP	SMARCC2	116967	17878164	Affinity Capture-MS
ADNP	SMARCC2	112485	17878164	Affinity Capture-MS
KDM5B	SMARCC2	115984	19336002	Affinity Capture-MS
KDM5B	SMARCC2	112485	19336002	Affinity Capture-MS
MCPH1	SMARCC2	122776	19525936	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
MCPH1	SMARCC2	112485	19525936	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
PBRM1	SMARCC2	112485	19650111	Affinity Capture-Western
PBRM1	SMARCC2	120490	19650111	Affinity Capture-Western
ARID1A	SMARCC2	112485	19650111	Affinity Capture-Western
ARID1A	SMARCC2	113894	19650111	Affinity Capture-Western
BANF1	SMARCC2	112485	19759913	Affinity Capture-MS
BANF1	SMARCC2	114342	19759913	Affinity Capture-MS
ARID1B	SMARCC2	112485	20086098	Affinity Capture-MS; Affinity Capture-Western
ARID1B	SMARCC2	121559	20086098	Affinity Capture-MS; Affinity Capture-Western

AutismKB 2.0

Annotation Details for SMARCC2