AutismKB 2.0

Annotation Details for SMARCE1


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Basic Information Top
Gene Symbol:SMARCE1 ( BAF57 )
Gene Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Band: 17q21.2
Quick LinksEntrez ID:6605; OMIM: 603111; Uniprot ID:SMCE1_HUMAN; ENSEMBL ID: ENSG00000073584; HGNC ID: 11109
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000228TAS-nuclear chromosome9435219
GO:0000790IDA-nuclear chromatin16217013
GO:0005634IDA-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0016514IDA-SWI/SNF complex8804307
GO:0017053IPI-transcriptional repressor complex12192000
GO:0043234IDA-protein complex16217013
GO:0071564ISS-npBAF complex-
GO:0071565ISS-nBAF complex-
GO ID Evidence Qualifier GO_term References
GO:0000978IDAcontributes_toRNA polymerase II core promoter proximal region sequence-specific DNA binding16217013
GO:0000980IDAcontributes_toRNA polymerase II distal enhancer sequence-specific DNA binding16217013
GO:0003682TAS-chromatin binding9435219
GO:0003713NAS-transcription coactivator activity8804307
GO:0003723IEA-RNA binding-
GO:0005515IPI-protein binding12192000
GO:0008080IDA-N-acetyltransferase activity12192000
GO:0016922IPI-ligand-dependent nuclear receptor binding17363140
GO:0031492IDAcontributes_tonucleosomal DNA binding16217013
GO:0047485IPI-protein N-terminus binding12917342
GO ID Evidence Qualifier GO_term References
GO:0006337IDA-nucleosome disassembly8895581
GO:0006338IDA-chromatin remodeling11726552
GO:0006357NAS-regulation of transcription from RNA polymerase II promoter8804307
GO:0016569IEA-covalent chromatin modification-
GO:0022008IEA-neurogenesis-
GO:0043044IDA-ATP-dependent chromatin remodeling16217013
GO:0045892IDA-negative regulation of transcription, DNA-templated12192000
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMARCE1ACTB1124899845365 18809673 Affinity Capture-MS; Affinity Capture-Western
SMARCE1ACTB1065759845365 18809673 Affinity Capture-MS; Affinity Capture-Western
SMARCE1ACTL6A1124899845365 18809673 Affinity Capture-MS; Affinity Capture-Western
SMARCE1ACTL6A1066019845365 18809673 Affinity Capture-MS; Affinity Capture-Western
SMARCE1AR11248915743818 18559499 Reconstituted Complex
SMARCE1AR10686215743818 18559499 Reconstituted Complex
SMARCE1CHD411248911003653 Affinity Capture-Western
SMARCE1CHD410753311003653 Affinity Capture-Western
SMARCE1ESR110840312145209 16538531 Affinity Capture-Western; Reconstituted Complex
SMARCE1ESR111248912145209 16538531 Affinity Capture-Western; Reconstituted Complex
SMARCE1ESR211248912145209 Reconstituted Complex
SMARCE1ESR210840412145209 Reconstituted Complex
SMARCE1GATA111248911018012 Reconstituted Complex
SMARCE1GATA110889311018012 Reconstituted Complex
SMARCE1NR3C111248912917342 Affinity Capture-Western
SMARCE1NR3C110916512917342 Affinity Capture-Western
SMARCE1HDAC111248912192000 Affinity Capture-Western
SMARCE1HDAC110931512192000 Affinity Capture-Western
SMARCE1HDAC210931612192000 Affinity Capture-Western
SMARCE1HDAC211248912192000 Affinity Capture-Western
SMARCE1NR4A111248919321449 Affinity Capture-MS
SMARCE1NR4A110940719321449 Affinity Capture-MS
SMARCE1MECP211248915696166 Affinity Capture-Western
SMARCE1MECP211036815696166 Affinity Capture-Western
SMARCE1PGR11126019609353 Reconstituted Complex
SMARCE1PGR11248919609353 Reconstituted Complex
SMARCE1RELB11248914743216 Affinity Capture-MS
SMARCE1RELB11190314743216 Affinity Capture-MS
SMARCE1DPF211248918809673 Affinity Capture-MS
SMARCE1DPF211190918809673 Affinity Capture-MS
SMARCE1REST11248912192000 Affinity Capture-Western
SMARCE1REST11191012192000 Affinity Capture-Western
SMARCE1SMARCA21124898895581 14559996 Affinity Capture-MS; Co-purification
SMARCE1SMARCA21124798895581 14559996 Affinity Capture-MS; Co-purification
SMARCE1SMARCA41124898895581 9845365 11003653 12192000 14559996 16287714 16940996 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCE1SMARCA41124818895581 9845365 11003653 12192000 14559996 16287714 16940996 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification
SMARCE1SMARCB11124828895581 9845365 16199878 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
SMARCE1SMARCB11124898895581 9845365 16199878 18809673 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
SMARCE1SMARCC11124899845365 16199878 16940996 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMARCE1SMARCC11124839845365 16199878 16940996 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMARCE1SMARCC21124899845365 16199878 16940996 18809673 19164553 19650111 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMARCE1SMARCC21124859845365 16199878 16940996 18809673 19164553 19650111 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMARCE1SMARCD111248916199878 18809673 Affinity Capture-MS; Reconstituted Complex
SMARCE1SMARCD111248616199878 18809673 Affinity Capture-MS; Reconstituted Complex
IKZF1SMARCE111248911003653 Affinity Capture-Western
IKZF1SMARCE111560411003653 Affinity Capture-Western
KLF1SMARCE111248911018012 Reconstituted Complex
KLF1SMARCE111590411018012 Reconstituted Complex
TFE3SMARCE111248911018012 Reconstituted Complex
TFE3SMARCE111288811018012 Reconstituted Complex
NCOA1SMARCE111420012145209 16538531 Reconstituted Complex
NCOA1SMARCE111248912145209 16538531 Reconstituted Complex
RCOR1SMARCE111248912192000 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RCOR1SMARCE111679612192000 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
STAT2SMARCE111265012244326 Affinity Capture-Western
STAT2SMARCE111248912244326 Affinity Capture-Western
BAZ1BSMARCE111449712837248 Affinity Capture-MS
BAZ1BSMARCE111248912837248 Affinity Capture-MS
PRMT5SMARCE111248914559996 Reconstituted Complex
PRMT5SMARCE111568814559996 Reconstituted Complex
SIN3BSMARCE111248914559996 Reconstituted Complex
SIN3BSMARCE111690114559996 Reconstituted Complex
SIN3ASMARCE111248914559996 Reconstituted Complex
SIN3ASMARCE111743914559996 Reconstituted Complex
CARM1SMARCE111576014729568 Affinity Capture-Western; Co-purification
CARM1SMARCE111248914729568 Affinity Capture-Western; Co-purification
NR0B2SMARCE111248915314177 Reconstituted Complex
NR0B2SMARCE111401215314177 Reconstituted Complex
ZMIZ2SMARCE111248916051670 Affinity Capture-Western
ZMIZ2SMARCE112370116051670 Affinity Capture-Western
ITCHSMARCE111248916055720 Affinity Capture-MS
ITCHSMARCE112374716055720 Affinity Capture-MS
ARID1ASMARCE111248916940996 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western
ARID1ASMARCE111389416940996 18809673 19650111 Affinity Capture-MS; Affinity Capture-Western
BRD7SMARCE111888318809673 Affinity Capture-MS
BRD7SMARCE111248918809673 Affinity Capture-MS
SMARCE1SMARCE111248918809673 Affinity Capture-MS
BCL7CSMARCE111469118809673 Affinity Capture-MS
BCL7CSMARCE111248918809673 Affinity Capture-MS
ARID2SMARCE111248918809673 Affinity Capture-MS; Affinity Capture-Western
ARID2SMARCE112821918809673 Affinity Capture-MS; Affinity Capture-Western
PBRM1SMARCE111248919650111 Affinity Capture-Western
PBRM1SMARCE112049019650111 Affinity Capture-Western
BANF1SMARCE111248919759913 Affinity Capture-MS
BANF1SMARCE111434219759913 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1927347
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-967'