AutismKB 2.0

Annotation Details for SNAP25


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Basic Information Top
Gene Symbol:SNAP25 ( FLJ23079,RIC-4,RIC4,SEC9,SNAP,SNAP-25,bA416N4.2,dJ1068F16.2 )
Gene Full Name: synaptosomal-associated protein, 25kDa
Band: 20p12.2
Quick LinksEntrez ID:6616; OMIM: 600322; Uniprot ID:SNP25_HUMAN; ENSEMBL ID: ENSG00000132639; HGNC ID: 11132
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737ISS-cytoplasm-
GO:0005802IEA-trans-Golgi network-
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0008021IEA-synaptic vesicle-
GO:0008076ISScolocalizes_withvoltage-gated potassium channel complex-
GO:0016020ISS-membrane-
GO:0030054IEA-cell junction-
GO:0030424IEA-axon-
GO:0030426ISS-growth cone-
GO:0031083IDAcolocalizes_withBLOC-1 complex19546860
GO:0031201IDA-SNARE complex12130530
GO:0031201ISS-SNARE complex-
GO:0031201TAS-SNARE complex15217342
GO:0031982IDAcolocalizes_withvesicle15459722
GO:0035579TAS-specific granule membrane-
GO:0036477IEA-somatodendritic compartment-
GO:0042734TAS-presynaptic membrane15217342
GO:0043005ISS-neuron projection-
GO:0043209IEA-myelin sheath-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0070032IBA-synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex-
GO:0070821TAS-tertiary granule membrane-
GO:0098794IEA-postsynapse-
GO ID Evidence Qualifier GO_term References
GO:0005484IBA-SNAP receptor activity-
GO:0005515IPI-protein binding8692999
GO:0017075IPI-syntaxin-1 binding12730201
GO:0048306ISS-calcium-dependent protein binding-
GO ID Evidence Qualifier GO_term References
GO:0001504NAS-neurotransmitter uptake8760387
GO:0007268NAS-chemical synaptic transmission8760387
GO:0007269TAS-neurotransmitter secretion-
GO:0007626IEA-locomotory behavior-
GO:0008306IEA-associative learning-
GO:0010975IEA-regulation of neuron projection development-
GO:0014047TAS-glutamate secretion-
GO:0016079TAS-synaptic vesicle exocytosis15217342
GO:0016081NAS-synaptic vesicle docking8760387
GO:0016082IBA-synaptic vesicle priming-
GO:0031629IBA-synaptic vesicle fusion to presynaptic active zone membrane-
GO:0031915IEA-positive regulation of synaptic plasticity-
GO:0043312TAS-neutrophil degranulation-
GO:0050796TAS-regulation of insulin secretion15537656
GO:0060291IEA-long-term synaptic potentiation-
GO:0098967IEA-exocytic insertion of neurotransmitter receptor to postsynaptic membrane-
GO:0099590IEA-neurotransmitter receptor internalization-
GO:1990926IEA-short-term synaptic potentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SNAP25STX21125007768895 8663154 Reconstituted Complex; Two-hybrid
SNAP25STX21083687768895 8663154 Reconstituted Complex; Two-hybrid
SNAP25KCNB110994712403834 Reconstituted Complex
SNAP25KCNB111250012403834 Reconstituted Complex
SNAP25KIF5B11250012475239 Reconstituted Complex; Two-hybrid
SNAP25KIF5B11000012475239 Reconstituted Complex; Two-hybrid
SNAP25ITSN111250010373452 Reconstituted Complex; Two-hybrid
SNAP25ITSN111235110373452 Reconstituted Complex; Two-hybrid
STX1ASNAP251126767553862 7768895 7961655 8663154 9852078 10195194 10449403 10954418 11524423 11832227 16169070 Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybrid
STX1ASNAP251125007553862 7768895 7961655 8663154 9852078 10195194 10449403 10954418 11524423 11832227 16169070 Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybrid
NAPASNAP251143057622514 Reconstituted Complex
NAPASNAP251125007622514 Reconstituted Complex
STX4SNAP251126797768895 8663154 9852078 10194441 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
STX4SNAP251125007768895 8663154 9852078 10194441 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
STX3SNAP251126787768895 8663154 9852078 Reconstituted Complex; Two-hybrid
STX3SNAP251125007768895 8663154 9852078 Reconstituted Complex; Two-hybrid
UNC13BSNAP251157598999968 Co-fractionation
UNC13BSNAP251125008999968 Co-fractionation
VAMP2SNAP251125009030619 11524423 11832227 Affinity Capture-Western; Co-crystal Structure; Far Western; Reconstituted Complex; Two-hybrid
VAMP2SNAP251127119030619 11524423 11832227 Affinity Capture-Western; Co-crystal Structure; Far Western; Reconstituted Complex; Two-hybrid
STX5SNAP251126809325254 Reconstituted Complex
STX5SNAP251125009325254 Reconstituted Complex
GOSR1SNAP251149039325254 Reconstituted Complex
GOSR1SNAP251125009325254 Reconstituted Complex
SNAPINSNAP2511250010195194 Affinity Capture-Western; Reconstituted Complex
SNAPINSNAP2511710110195194 Affinity Capture-Western; Reconstituted Complex
SRCIN1SNAP2512327510625663 Reconstituted Complex; Two-hybrid
SRCIN1SNAP2511250010625663 Reconstituted Complex; Two-hybrid
SYT1SNAP2511250010692432 12062043 Reconstituted Complex
SYT1SNAP2511272310692432 12062043 Reconstituted Complex
SYT3SNAP2511250010692432 Reconstituted Complex
SYT3SNAP2512398510692432 Reconstituted Complex
SCAMP1SNAP2511489910777571 Reconstituted Complex
SCAMP1SNAP2511250010777571 Reconstituted Complex
STX12SNAP2511719110886332 Affinity Capture-Western
STX12SNAP2511250010886332 Affinity Capture-Western
TRIM9SNAP2512528011524423 Affinity Capture-Western; Reconstituted Complex
TRIM9SNAP2511250011524423 Affinity Capture-Western; Reconstituted Complex
CPLX1SNAP2511602811832227 12200427 Co-crystal Structure; Reconstituted Complex
CPLX1SNAP2511250011832227 12200427 Co-crystal Structure; Reconstituted Complex
VAMP7SNAP2511250012853575 Reconstituted Complex
VAMP7SNAP2511271212853575 Reconstituted Complex
PRRT2SNAP2511250016169070 Two-hybrid
PRRT2SNAP2512518816169070 Two-hybrid
STX11SNAP2511422416169070 16189514 Two-hybrid
STX11SNAP2511250016169070 16189514 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
SNAPINSNAP2520000315635093 SNAP25 interacts with Snapin.
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SNAP25SNAP25, SNAP25_DdeI, SNAP25_MnlI, SNAP25_P1, SNAP25_T1065G, SNAP25_T1069C, SNAP25_TaiI, rs1013044, rs1051312, rs1158497, rs1158827, rs12480983, rs12626080, rs13044668, rs16991263, rs16991334, rs1889189, rs1984830, rs1984831, rs2076239, rs2076240, rs2225635, rs2284297, rs2284299, rs2284300, rs2327264, rs2327265, rs2327266, rs2327267, rs2423486, rs2423487, rs3025866, rs3025873, rs3025879, rs3025883, rs362547, rs362548, rs362549, rs362551, rs362552, rs362562, rs362564, rs362567, rs362568, rs362569, rs362570, rs362582, rs362584, rs362585, rs362588, rs362590, rs362592, rs362596, rs362599, rs362600, rs362602, rs362604, rs362605, rs362987, rs362988, rs362990, rs362991, rs362993, rs362995, rs362998, rs362999, rs363004, rs363005, rs363006, rs363010, rs363011, rs363012, rs363013, rs363014, rs363015, rs363016, rs363018, rs363020, rs363021, rs363022, rs363026, rs363029, rs363031, rs363032, rs363035, rs363036, rs363037, rs363038, rs363039, rs363043, rs363050, rs363052, rs363053, rs3746544, rs3787283, rs3787300, rs3787303, rs4510293, rs4813023, rs4813024, rs4813921, rs4813927, rs6032824, rs6032826, rs6032832, rs6032845, rs6032846, rs6039769, rs6039783, rs6039792, rs6039793, rs6039795, rs6039806, rs6039807, rs6039820, rs6074113, rs6074121, rs6077693, rs6077697, rs6077699, rs6077712, rs6077718, rs6077719, rs6077722, rs6077729, rs6104567, rs6104571, rs6108461, rs6108463, rs6108464, rs6108466, rs6133845, rs6133852, rs6133855, rs7268664, rs8116632, rs8119844, rs8636, ss107056528 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:98331
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-980526-392'